New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis
of multiple sclerosis. The use of imaging for demonstration of dissemination of central …

The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in research
and clinical practice. Scientific advances in the past 7 years suggest that they might no …

New diagnostic criteria for multiple sclerosis integrating magnetic resonance image
assessment with clinical and other paraclinical methods were introduced in 2001. The “McDonald …

Accurate clinical course descriptions (phenotypes) of multiple sclerosis (MS) are important
for communication, prognostication, design and recruitment of clinical trials, and treatment …

Evidence concerning anatomical connectivities in the human brain is sparse and based largely
on limited post-mortem observations. Diffusion tensor imaging has previously been used …

Multiple sclerosis (MS) is one of the world's most common neurologic disorders, and in
many countries it is the leading cause of nontraumatic neurologic disability in young adults. …

Background In patients with isolated syndromes that are clinically suggestive of multiple
sclerosis, such as optic neuritis or brain-stem or spinal cord syndromes, the presence of lesions …

Magnetic resonance imaging (MRI) monitoring of disease progression in multiple sclerosis
is limited by the lack of correlation of abnormalities seen on T2‐weighted imaging, and …

Axonal loss is thought to be a likely cause of persistent disability after a multiple sclerosis
relapse; therefore, noninvasive in vivo markers specific for axonal loss are needed. We used …

Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming
available in the past years. There is a need for a reference tool compiling current data to aid …