User profiles for Alan Koh

Alan Koh

- Verified email at lms.mrc.ac.uk - Cited by 530

Alan K Koh

- Verified email at ntu.edu.sg - Cited by 162

[PDF][PDF] Condensin-and replication-mediated bacterial chromosome folding and origin condensation revealed by Hi-C and super-resolution imaging

M Marbouty, A Le Gall, DI Cattoni, A Cournac, A Koh… - Molecular cell, 2015 - cell.com
Chromosomes of a broad range of species, from bacteria to mammals, are structured by
large topological domains whose precise functional roles and regulatory mechanisms remain …

A widespread toxin− antitoxin system exploiting growth control via alarmone signaling

…, C Stavropoulos, SRA Oliveira, A Koh… - Proceedings of the …, 2020 - National Acad Sciences
Under stressful conditions, bacterial RelA-SpoT Homolog (RSH) enzymes synthesize the
alarmone (p)ppGpp, a nucleotide second messenger. (p)ppGpp rewires bacterial transcription …

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

GLM Fisher, CL Pastrana, VA Higman, A Koh… - Elife, 2017 - elifesciences.org
10.7554/eLife.28086.001 The ParB protein forms DNA bridging interactions around parS to
condense DNA and earmark the bacterial chromosome for segregation. The molecular …

[HTML][HTML] Multiple Regulatory Systems Coordinate DNA Replication with Cell Growth in Bacillus subtilis

H Murray, A Koh - PLoS genetics, 2014 - journals.plos.org
In many bacteria the rate of DNA replication is linked with cellular physiology to ensure that
genome duplication is coordinated with growth. Nutrient-mediated growth rate control of DNA …

Diversity of shareholder stewardship in asia: faux convergence

G Goto, AK Koh, DW Puchniak - Vand. J. Transnat'l L., 2020 - HeinOnline
Since the UK adopted the world's first stewardship code in 2010, stewardship codes have
proliferated across Asia. Given the UK Code's prominence, it is tempting to assume that every …

[HTML][HTML] Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans

…, A Pandey, L Zhao, R Schendel, A Koh… - Nature …, 2023 - nature.com
G protein-coupled receptors (GPCRs) mediate responses to various extracellular and
intracellular cues. However, the large number of GPCR genes and their substantial functional …

Conformation control of the histidine kinase BceS of Bacillus subtilis by its cognate ABC‐transporter facilitates need‐based activation of antibiotic resistance

A Koh, MJ Gibbon, MW Van der Kamp… - Molecular …, 2021 - Wiley Online Library
Bacteria closely control gene expression to ensure optimal physiological responses to their
environment. Such careful gene expression can minimize the fitness cost associated with …

Ocular trauma injuries: a 1-year surveillance study in the University of Malaya Medical Centre, Malaysia. 2008

TKW Soong, A Koh, V Subrayan, AVP Loo - Graefe's archive for clinical …, 2011 - Springer
Purpose To describe the epidemiology of ocular injuries presenting to the University Malaya
Medical Centre (UMMC), Kuala Lumpur, Malaysia. Design Prospective analysis of all ocular …

Crystal structure of NucB, a biofilm-degrading endonuclease

A Baslé, L Hewitt, A Koh, HK Lamb… - Nucleic Acids …, 2018 - academic.oup.com
Bacterial biofilms are a complex architecture of cells that grow on moist interfaces, and are
held together by a molecular glue of extracellular proteins, sugars and nucleic acids. Biofilms …

Reconstructing the reflective loss principle

AK Koh - Journal of Corporate Law Studies, 2016 - Taylor & Francis
When a company suffers loss due to a wrongful act perpetrated against the company, the
company’s shareholders suffer where the value of their shares or dividends decreases. …