Epithelial regeneration is critical for barrier maintenance and organ function after intestinal
injury. The intestinal stem cell (ISC) niche provides Wnt, Notch and epidermal growth factor (…

Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T
helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs). …

The relationship between intestinal microbiota composition and acute graft-versus-host disease
(GVHD) after allogeneic blood/marrow transplantation (allo-BMT) is not well understood. …

Despite a growing understanding of the link between intestinal inflammation and resident gut
microbes, longitudinal studies of human flora before initial onset of intestinal inflammation …

Little is known about the maintenance of intestinal stem cells (ISCs) and progenitors during
immune-mediated tissue damage or about the susceptibility of transplant recipients to tissue …

Intestinal bacteria may modulate the risk of infection and graft-versus-host disease (GVHD)
after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Allo-HSCT recipients …

Endogenous thymic regeneration is a crucial function that allows for renewal of immune
competence after stress, infection, or immunodepletion. However, the mechanisms governing …

The spectrum of somatic alterations in hematologic malignancies includes substitutions,
insertions/deletions (indels), copy number alterations (CNAs), and a wide range of gene fusions; …

The bZIP transcription factor Nfil3 (also known as E4BP4) is required for the development of
natural killer (NK) cells and type 1 innate lymphoid cells (ILC1s). We find that Nfil3 plays a …

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative therapy
for hematological malignancies. However, graft-versus-host disease (GVHD) and relapse …