User profiles for Alberto Alape
Alberto Alape-GirónUniversidad de Costa Rica Verified email at ucr.ac.cr Cited by 4039 |
Characterization of 'basparin A,'a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces …
A prothrombin activator, named ‘basparin A,’ was isolated from the venom of the crotaline
snake Bothrops asper, the species responsible for the majority of snakebite cases in Central …
snake Bothrops asper, the species responsible for the majority of snakebite cases in Central …
[HTML][HTML] Development and characterization of two equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19
…, R Sanchez, JM Gutiérrez, C Diaz, A Alape - Scientific reports, 2021 - nature.com
In the current global emergency due to SARS-CoV-2 outbreak, passive immunotherapy
emerges as a promising treatment for COVID-19. Among animal-derived products, equine …
emerges as a promising treatment for COVID-19. Among animal-derived products, equine …
Snake Venomics of the Lancehead Pitviper Bothrops asper: Geographic, Individual, and Ontogenetic Variations
A Alape-Girón, L Sanz, J Escolano… - Journal of proteome …, 2008 - ACS Publications
We report the comparative proteomic characterization of the venoms of adult and newborn
specimens of the lancehead pitviper Bothrops asper from two geographically isolated …
specimens of the lancehead pitviper Bothrops asper from two geographically isolated …
Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic …
…, Y Angulo, B Lomonte, A Alape-Girón… - Journal of proteome …, 2010 - ACS Publications
We report a comparative venomic and antivenomic characterization of the venoms of
newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the …
newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the …
Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming
Snakebite envenoming represents a neglected tropical disease that has a heavy public
health impact, particularly in Asia, Africa and Latin America. A global initiative, aimed at …
health impact, particularly in Asia, Africa and Latin America. A global initiative, aimed at …
Bacterial sphingomyelinases and phospholipases as virulence factors
…, C Naylor, A Alape-Girón… - Microbiology and …, 2016 - Am Soc Microbiol
Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases
which are usually surface associated or secreted by a wide variety of Gram-positive and …
which are usually surface associated or secreted by a wide variety of Gram-positive and …
[PDF][PDF] Comparative study on the ability of IgG and F (ab') 2 antivenoms to neutralize lethal and myotoxic effects induced by Micrurus nigrocinctus (coral snake) venom.
A comparative study was performed on the ability of IgG and F (ab) 2 antivenoms to neutralize
lethal and myotoxic activities of Micrurus nigrocinctus venom. Both antivenoms were …
lethal and myotoxic activities of Micrurus nigrocinctus venom. Both antivenoms were …
Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue‐damaging activities
BaP1 is a 22.7‐kD P‐I‐type zinc‐dependent metalloproteinase isolated from the venom of
the snake Bothrops asper, a medically relevant species in Central America. This enzyme …
the snake Bothrops asper, a medically relevant species in Central America. This enzyme …
Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses
The application of proteomic tools to the study of snake venoms has led to an impressive
growth in the knowledge about their composition (venomics), immunogenicity (antivenomics), …
growth in the knowledge about their composition (venomics), immunogenicity (antivenomics), …
Venomic and Antivenomic Analyses of the Central American Coral Snake, Micrurus nigrocinctus (Elapidae)
J Fernández, A Alape-Girón, Y Angulo… - Journal of proteome …, 2011 - ACS Publications
The proteome of the venom of Micrurus nigrocinctus (Central American coral snake) was
analyzed by a “venomics” approach. Nearly 50 venom peaks were resolved by RP-HPLC, …
analyzed by a “venomics” approach. Nearly 50 venom peaks were resolved by RP-HPLC, …