Limitations on the number of unique protein and DNA molecules that can be characterized
microscopically in a single tissue specimen impede advances in understanding the biological …

Intestinal tuft cells are a rare, poorly understood cell type recently shown to be a critical
mediator of type 2 immune response to helminth infection. Here, we present advances in …

At GE Research, we are combining “physics” with artificial intelligence and machine
learning to advance manufacturing design, processing, and inspection, turning innovative …

Epithelial organ morphogenesis involves reciprocal interactions between epithelial and
mesenchymal cell types to balance progenitor cell retention and expansion with cell …

Over the last 15 years, advances in immunofluorescence-imaging based cycling methods,
antibody conjugation methods, and automated image processing have facilitated the …

A systemic analysis of the tumor-immune interactions within the heterogeneous tumor
microenvironment is of particular importance for understanding the antitumor immune response. …

The challenges faced in analyzing optical imaging data from neurons include a low signal-to-noise
ratio of the acquired images and the multiscale nature of the tubular structures that …

Degeneration of the primary motor cortex is a defining feature of amyotrophic lateral sclerosis
(ALS), which is associated with the accumulation of microscopic protein aggregates in …

Heterogeneous patterns of mutations and RNA expression have been well documented in
invasive cancers. However, technological challenges have limited the ability to study …

Cancer cells’ ability to inhibit apoptosis is key to malignant transformation and limits response
to therapy. Here, we performed multiplexed immunofluorescence analysis on tissue …