Many population genetics tools employ composite likelihoods, because fully modeling genomic
linkage is challenging. But traditional approaches to estimating parameter uncertainties …

We implement a rare-event sampling scheme for quantifying the rate of thermally activated
nonadiabatic transitions in the condensed phase. Our Quantum mechanics/molecular …

Background The allele frequency spectrum (AFS) consists of counts of the number of single
nucleotide polymorphism (SNP) loci with derived variants present at each given frequency in …

The effect of a mutation on fitness may differ between populations depending on environmental
and genetic context, but little is known about the factors that underlie such differences. …

We investigate rates of electron transfer for generalized Anderson–Holstein models in the
limit of weak molecule–metal coupling, using both surface hopping and electronic friction …

The distribution of mutational effects on fitness is central to evolutionary genetics. Typical
univariate distributions, however, cannot model the effects of multiple mutations at the same site…

We investigate rates of proton-coupled electron transfer (PCET) in potential sweep experiments
for a generalized Anderson–Holstein model with the inclusion of a quantized proton …

We present a computational approach to simulate linear sweep and cyclic voltammetry
experiments that does not require a discretized grid in space to quantify diffusion. By using a …

We analyze different stochastic approaches for simulating electron transfer and potential
sweep experiments in diffusive multidimensional electrochemical systems. In particular, we …

The effect of a mutation on fitness may differ between populations, depending on environmental
and genetic context. Experimental studies have shown that such differences exist, but …