User profiles for Alejandro Rivera-Madera
 | Alejandro Rivera-MaderaUndergraduate Student, University of Puerto Rico at Cayey Verified email at upr.edu Cited by 5 |
[HTML][HTML] Disease-associated non-coding variants alter NKX2-5 DNA-binding affinity
EG Peña-Martínez, A Rivera-Madera… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Genome-wide association studies (GWAS) have mapped over 90 % of disease- or trait-associated
variants within the non-coding genome, like cis-regulatory elements (CREs). Non-…
variants within the non-coding genome, like cis-regulatory elements (CREs). Non-…
[HTML][HTML] Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach
…, DA Pomales-Matos, A Rivera-Madera… - Journal of Biological …, 2023 - ASBMB
Cardiovascular diseases (CVDs) are the leading cause of death worldwide and are heavily
influenced by genetic factors. Genome-wide association studies have mapped >90% of CVD-…
influenced by genetic factors. Genome-wide association studies have mapped >90% of CVD-…
Abstract 2307 Evaluating the thermal stability of congenital heart diseases-associated TBX5 missense mutants
A Rivera-Madera, E Peña-Martínez… - Journal of Biological …, 2024 - ASBMB
During the starvation and differentiation of cells, the process of autophagy is important for the
survival of kinetoplastids, which suggests that the autophagic pathway could be a target for …
survival of kinetoplastids, which suggests that the autophagic pathway could be a target for …
[HTML][HTML] Prioritizing Cardiovascular Disease-Associated Variants Altering NKX2–5 Binding through an Integrative Computational Approach
…, DA Pomales-Matos, A Rivera-Madera… - medRxiv, 2023 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) are the leading cause of death worldwide and are heavily
influenced by genetic factors. Genome-wide association studies (GWAS) have mapped> 90…
influenced by genetic factors. Genome-wide association studies (GWAS) have mapped> 90…
[HTML][HTML] Coding and non-coding elements comprise a regulatory network controlling transcription in Kaposi's sarcoma-associated herpesvirus
Gene regulation in eukaryotes relies on many mechanisms for optimal expression, including
both protein transcription factors and DNA regulatory elements. CRISPR-based screens of …
both protein transcription factors and DNA regulatory elements. CRISPR-based screens of …
Abstract 1677 Implementing a Support Vector Machine-based Computational Method to Prioritize Cardiovascular Disease-Risk Variants
…, E Peña-Martínez, A Rivera-Madera… - Journal of Biological …, 2024 - ASBMB
Edwin Peña-Martínez, Alejandro Rivera-Madera, Jean Messon-Bird, Joshua Medina-
Feliciano, Leandro Sanabria-Alberto, Adriana Barreiro-Rosario, Jeancarlos Rivera-Del …
Feliciano, Leandro Sanabria-Alberto, Adriana Barreiro-Rosario, Jeancarlos Rivera-Del …
Abstract 1473 Integrating Machine Learning and Functional Genomics to Prioritize CVD-associated Mutations Altering NKX2-5 and TBX5 DNA Binding
…, D Pomales-Matos, A Rivera-Madera… - Journal of Biological …, 2024 - ASBMB
Diego Pomales-Matos, Alejandro Rivera-Madera, Jean Messon-Bird, Joshua Medina-
Feliciano, Leandro Sanabria-Alberto, Adriana Barreiro-Rosario, Jeancarlos Rivera-Del …
Feliciano, Leandro Sanabria-Alberto, Adriana Barreiro-Rosario, Jeancarlos Rivera-Del …
Abstract 1489 Congenital Heart Disease-associated Mutations Alter TBX5-DNA Binding Affinity
…, D Pomales-Matos, A Rivera-Madera… - Journal of Biological …, 2024 - ASBMB
Congenital heart diseases (CHDs) are the most common birth defect, affecting 1 in every 100
liveborn infants. CHDs are characterized by structural abnormalities that occur during heart …
liveborn infants. CHDs are characterized by structural abnormalities that occur during heart …
Abstract 1638 Bioinformatic Prioritization of Cardiovascular Disease-Linked Variants Modulating TBX5 Binding
…, D Pomales-Matos, A Rivera-Madera… - Journal of Biological …, 2024 - ASBMB
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, responsible for
approximately 17.9 million lives each year. Genome-wide association studies (GWAS) have …
approximately 17.9 million lives each year. Genome-wide association studies (GWAS) have …
[CITATION][C] Cardiovascular-Disease/Trait Associated Variants Alter NKX2-5 DNA Binding Affinity
…, D Pomales-Matos, A Rivera-Madera… - Journal of Biological …, 2023 - Elsevier