Expansion microscopy enables nanoimaging with conventional microscopes by physically
and isotropically magnifying preserved biological specimens embedded in a crosslinked …

Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as
new excitatory optogenetic tools not only in neuroscience, but also in other areas, including …

The improvement of preclinical cardiotoxicity testing, discovery of new ion-channel-targeted
drugs, and phenotyping and use of stem cell-derived cardiomyocytes and other biologics all …

In nature, macroscopic excitation waves 1 , 2 are found in a diverse range of settings
including chemical reactions, metal rust, yeast, amoeba and the heart and brain. In the case of …

In complex multicellular systems, such as the brain or the heart, the ability to selectively
perturb and observe the response of individual components at the cellular level and with …

Stimulated Raman scattering (SRS) microscopy is an emerging technology that provides
high chemical specificity for endogenous biomolecules and can circumvent common …

High-throughput in vitro drug assays have been impacted by recent advances in human
induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) technology and by contact-…

Combined optogenetic stimulation and optical imaging permit scalable, contact-free high-throughput
probing of cellular electrophysiology and optimization of stem-cell derived excitable …

Super‐resolution optical imaging tools are crucial in microbiology to understand the complex
structures and behavior of microorganisms such as bacteria, fungi, and viruses. However, …

The ability to perform precise, spatially localized actuation and measurements of electrical
activity in the heart is crucial in understanding cardiac electrophysiology and devising new …