Chromosome inheritance depends on centromeres, epigenetically specified regions of
chromosomes. While conventional human centromeres are known to be built of long tandem …

Motion is a key characteristic of every form of life 1 . Even at the microscale, it has been reported
that colonies of bacteria can generate nanomotion on mechanical cantilevers 2 , but the …

The replication and transfer of genomic material from a cell to its progeny are vital processes
in all living systems. Here we visualize the process of chromosome replication in widened E…

Although the physical properties of chromosomes, including their morphology, mechanics,
and dynamics are crucial for their biological function, many basic questions remain …

The process of DNA segregation, the redistribution of newly replicated genomic material to
daughter cells, is a crucial step in the life cycle of all living systems. Here, we review DNA …

Mycobacterium tuberculosis secretes multiple virulence factors during infection via the
general Sec and Tat pathways, and via specialized ESX secretion systems, also referred to as …

The bacterial chromosome is spatially organized through protein-mediated compaction,
supercoiling, and cell-boundary confinement. Structural Maintenance of Chromosomes (SMC) …

DNA adopts different conformations based on its environment. We reveal conditions that
either preserve the DNA’s physiological B-conformation, even upon its placement in UHV, or …

Bacterial chromosome has a compact structure that dynamically changes its shape in
response to bacterial growth rate and growth phase. Determining how chromatin remains …

Nucleoid-associated proteins (NAPs) are a class of highly abundant DNA-binding proteins
in bacteria and archaea. While both the composition and relative abundance of the NAPs …