User profiles for Aleksey Zimin

Aleksey V Zimin

Associate Research Scientist, Department of Biomedical Engineering, Johns Hopkins …
Verified email at jhu.edu
Cited by 19268

[HTML][HTML] A whole-genome assembly of the domestic cow, Bos taurus

AV Zimin, AL Delcher, L Florea, DR Kelley, MC Schatz… - Genome biology, 2009 - Springer
Background The genome of the domestic cow, Bos taurus, was sequenced using a mixture
of hierarchical and whole-genome shotgun sequencing methods. Results We have …

The MaSuRCA genome assembler

AV Zimin, G Marçais, D Puiu, M Roberts… - …, 2013 - academic.oup.com
Motivation: Second-generation sequencing technologies produce high coverage of the
genome by short reads at a low cost, which has prompted development of new assembly …

[HTML][HTML] MUMmer4: A fast and versatile genome alignment system

…, R Coston, SL Salzberg, A Zimin - PLoS computational …, 2018 - journals.plos.org
The MUMmer system and the genome sequence aligner nucmer included within it are among
the most widely used alignment packages in genomics. Since the last major release of …

[HTML][HTML] A draft human pangenome reference

…, FF Tricomi, J Wagner, B Walenz, JMD Wood, AV Zimin… - Nature, 2023 - nature.com
Here the Human Pangenome Reference Consortium presents a first draft of the human
pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of …

A local ensemble Kalman filter for atmospheric data assimilation

E Ott, BR Hunt, I Szunyogh, AV Zimin… - Tellus A: Dynamic …, 2004 - Taylor & Francis
In this paper, we introduce a new, local formulation of the ensemble Kalman filter approach
for atmospheric data assimilation. Our scheme is based on the hypothesis that, when the …

[HTML][HTML] Transcriptome assembly from long-read RNA-seq alignments with StringTie2

S Kovaka, AV Zimin, GM Pertea, R Razaghi… - Genome biology, 2019 - Springer
RNA sequencing using the latest single-molecule sequencing instruments produces reads
that are thousands of nucleotides long. The ability to assemble these long reads can greatly …

[HTML][HTML] The Atlantic salmon genome provides insights into rediploidization

…, T Nome, TR Hvidsten, JS Leong, DR Minkley, A Zimin… - Nature, 2016 - nature.com
The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific
fourth vertebrate whole-genome duplication, Ss4R) provides unique …

GAGE: A critical evaluation of genome assemblies and assembly algorithms

SL Salzberg, AM Phillippy, A Zimin, D Puiu… - Genome …, 2012 - genome.cshlp.org
New sequencing technology has dramatically altered the landscape of whole-genome
sequencing, allowing scientists to initiate numerous projects to decode the genomes of previously …

De novo assembly of the cattle reference genome with single-molecule sequencing

…, CG Elsik, E Tseng, TN Rowan, WY Low, A Zimin… - …, 2020 - academic.oup.com
Background Major advances in selection progress for cattle have been made following the
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …

[HTML][HTML] Genome sequence of the progenitor of the wheat D genome Aegilops tauschii

…, L Xiao, OD Anderson, S Ouyang, Y Liang, AV Zimin… - Nature, 2017 - nature.com
Aegilops tauschii is the diploid progenitor of the D genome of hexaploid wheat 1 (Triticum
aestivum, genomes AABBDD) and an important genetic resource for wheat 2 , 3 , 4 . The large …