User profiles for Aleksey Zimin
Aleksey V ZiminAssociate Research Scientist, Department of Biomedical Engineering, Johns Hopkins … Verified email at jhu.edu Cited by 19268 |
[HTML][HTML] A whole-genome assembly of the domestic cow, Bos taurus
Background The genome of the domestic cow, Bos taurus, was sequenced using a mixture
of hierarchical and whole-genome shotgun sequencing methods. Results We have …
of hierarchical and whole-genome shotgun sequencing methods. Results We have …
The MaSuRCA genome assembler
Motivation: Second-generation sequencing technologies produce high coverage of the
genome by short reads at a low cost, which has prompted development of new assembly …
genome by short reads at a low cost, which has prompted development of new assembly …
[HTML][HTML] MUMmer4: A fast and versatile genome alignment system
…, R Coston, SL Salzberg, A Zimin - PLoS computational …, 2018 - journals.plos.org
The MUMmer system and the genome sequence aligner nucmer included within it are among
the most widely used alignment packages in genomics. Since the last major release of …
the most widely used alignment packages in genomics. Since the last major release of …
[HTML][HTML] A draft human pangenome reference
Here the Human Pangenome Reference Consortium presents a first draft of the human
pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of …
pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of …
A local ensemble Kalman filter for atmospheric data assimilation
In this paper, we introduce a new, local formulation of the ensemble Kalman filter approach
for atmospheric data assimilation. Our scheme is based on the hypothesis that, when the …
for atmospheric data assimilation. Our scheme is based on the hypothesis that, when the …
[HTML][HTML] Transcriptome assembly from long-read RNA-seq alignments with StringTie2
RNA sequencing using the latest single-molecule sequencing instruments produces reads
that are thousands of nucleotides long. The ability to assemble these long reads can greatly …
that are thousands of nucleotides long. The ability to assemble these long reads can greatly …
[HTML][HTML] The Atlantic salmon genome provides insights into rediploidization
The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific
fourth vertebrate whole-genome duplication, Ss4R) provides unique …
fourth vertebrate whole-genome duplication, Ss4R) provides unique …
GAGE: A critical evaluation of genome assemblies and assembly algorithms
New sequencing technology has dramatically altered the landscape of whole-genome
sequencing, allowing scientists to initiate numerous projects to decode the genomes of previously …
sequencing, allowing scientists to initiate numerous projects to decode the genomes of previously …
De novo assembly of the cattle reference genome with single-molecule sequencing
Background Major advances in selection progress for cattle have been made following the
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …
[HTML][HTML] Genome sequence of the progenitor of the wheat D genome Aegilops tauschii
…, L Xiao, OD Anderson, S Ouyang, Y Liang, AV Zimin… - Nature, 2017 - nature.com
Aegilops tauschii is the diploid progenitor of the D genome of hexaploid wheat 1 (Triticum
aestivum, genomes AABBDD) and an important genetic resource for wheat 2 , 3 , 4 . The large …
aestivum, genomes AABBDD) and an important genetic resource for wheat 2 , 3 , 4 . The large …