[PDF][PDF] Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology

…, SV Gupta, F Jin, G Piumatti, GL Presti, AF Pellanda… - Cell, 2020 - cell.com
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-CoV-2
infection is crucial for understanding immune protection and identifying targets for …

[HTML][HTML] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

…, A Ceschi, P Ferrari, PE Cippà, A Franzetti-Pellanda… - Nature, 2022 - nature.com
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …

[HTML][HTML] Sensitivity of SARS-CoV-2 B. 1.1. 7 to mRNA vaccine-elicited antibodies

…, E Cameroni, G Snell, MS Pizzuto, AF Pellanda… - Nature, 2021 - nature.com
Transmission of SARS-CoV-2 is uncontrolled in many parts of the world; control is compounded
in some areas by the higher transmission potential of the B.1.1.7 variant 1 , which has …

SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern

…, MS Pizzuto, SB Guastalla, G Bona, AF Pellanda… - Science, 2021 - science.org
A novel variant of concern (VOC) named CAL.20C (B.1.427/B.1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide, W152C …

[HTML][HTML] Neutralization, effector function and immune imprinting of Omicron variants

…, P Cippà, A Ceschi, P Ferrari, A Franzetti-Pellanda… - Nature, 2023 - nature.com
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain 1 (RBD) of the spike protein. The effects of these mutations …

[HTML][HTML] Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course

…, A Mantovani, C Garzoni, A Franzetti-Pellanda… - Nature …, 2023 - nature.com
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse
symptoms, which can persist for months. While antiviral antibodies are protective, those targeting …

Volumetric-modulated arc radiotherapy for carcinomas of the anal canal: A treatment planning comparison with fixed field IMRT

A Clivio, A Fogliata, A Franzetti-Pellanda… - Radiotherapy and …, 2009 - Elsevier
PURPOSE: A treatment planning study was performed to compare volumetric-modulated
arc radiotherapy against conventional fixed field IMRT. MATERIALS AND METHODS: CT …

Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2

…, S Jovic, L Perez, R Cacciatore, T Terrot, AF Pellanda… - Science, 2021 - science.org
The identification of CD4 + T cell epitopes is instrumental for the design of subunit vaccines
for broad protection against coronaviruses. Here, we demonstrate in COVID-19–recovered …

Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein

…, D Fernandez, F Baldanti, A Franzetti-Pellanda… - Science …, 2023 - science.org
Emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
diminishes the efficacy of vaccines and antiviral monoclonal antibodies. Continued development …

[HTML][HTML] SARS-CoV-2 B. 1.1. 7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies

…, E Cameroni, G Snell, MS Pizzuto, AF Pellanda… - MedRxiv, 2021 - ncbi.nlm.nih.gov
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) transmission is uncontrolled
in many parts of the world, compounded in some areas by higher transmission potential …