User profiles for Alessandro Furlan

Alessandro Furlan

- Verified email at ki.se - Cited by 9248

Alessandro Furlan

- Verified email at pitt.edu - Cited by 4988

Alessandro FURLAN

- Verified email at univ-lille.fr - Cited by 990

Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla

A Furlan, V Dyachuk, ME Kastriti, L Calvo-Enrique… - Science, 2017 - science.org
INTRODUCTION Circulating adrenaline can have profound effects on the body’s “inner world,”
adjusting levels depending on demand to maintain organ and bodily homeostasis during …

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

D Usoskin, A Furlan, S Islam, H Abdo… - Nature …, 2015 - nature.com
The primary sensory system requires the integrated function of multiple cell types, although
its full complexity remains unclear. We used comprehensive transcriptome analysis of 622 …

[PDF][PDF] Molecular architecture of the mouse nervous system

…, LE Borm, G La Manno, S Codeluppi, A Furlan… - Cell, 2018 - cell.com
The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a million …

RNA velocity of single cells

…, K Lidschreiber, ME Kastriti, P Lönnerberg, A Furlan… - Nature, 2018 - nature.com
RNA abundance is a powerful indicator of the state of individual cells. Single-cell RNA
sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and …

Molecular architecture of the developing mouse brain

G La Manno, K Siletti, A Furlan, D Gyllborg, E Vinsland… - Nature, 2021 - nature.com
The mammalian brain develops through a complex interplay of spatial cues generated by
diffusible morphogens, cell–cell interactions and intrinsic genetic programs that result in …

Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity

…, JM Karlsson, K Lee, KT Bae, A Furlan… - Science translational …, 2011 - science.org
Obesity increases the risk of adverse outcomes during acute critical illnesses such as burns,
severe trauma, and acute pancreatitis. Although individuals with more body fat and higher …

Glial origin of mesenchymal stem cells in a tooth model system

…, C Konstantinidou, V Dyachuk, M Kaucka, A Furlan… - Nature, 2014 - nature.com
Mesenchymal stem cells occupy niches in stromal tissues where they provide sources of
cells for specialized mesenchymal derivatives during growth and repair 1 . The origins of …

ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity

S Julien, E Adriaenssens, K Ottenberg, A Furlan… - …, 2006 - academic.oup.com
Sialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers, including
breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-…

Parasympathetic neurons originate from nerve-associated peripheral glial progenitors

V Dyachuk, A Furlan, MK Shahidi, M Giovenco… - Science, 2014 - science.org
The peripheral autonomic nervous system reaches far throughout the body and includes
neurons of diverse functions, such as sympathetic and parasympathetic. We show that the …

Short-term mortality in acute pulmonary embolism: clot burden and signs of right heart dysfunction at CT pulmonary angiography

A Furlan, A Aghayev, CCH Chang, A Patil, KN Jeon… - Radiology, 2012 - pubs.rsna.org
Purpose To assess the correlation between volumetric measurements of clot, semiquantitative
clot burden indexes, and signs of right heart dysfunction at computed tomographic (CT) …