Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla
INTRODUCTION Circulating adrenaline can have profound effects on the body’s “inner world,”
adjusting levels depending on demand to maintain organ and bodily homeostasis during …
adjusting levels depending on demand to maintain organ and bodily homeostasis during …
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
The primary sensory system requires the integrated function of multiple cell types, although
its full complexity remains unclear. We used comprehensive transcriptome analysis of 622 …
its full complexity remains unclear. We used comprehensive transcriptome analysis of 622 …
[PDF][PDF] Molecular architecture of the mouse nervous system
The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a million …
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a million …
RNA velocity of single cells
…, K Lidschreiber, ME Kastriti, P Lönnerberg, A Furlan… - Nature, 2018 - nature.com
RNA abundance is a powerful indicator of the state of individual cells. Single-cell RNA
sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and …
sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and …
Molecular architecture of the developing mouse brain
The mammalian brain develops through a complex interplay of spatial cues generated by
diffusible morphogens, cell–cell interactions and intrinsic genetic programs that result in …
diffusible morphogens, cell–cell interactions and intrinsic genetic programs that result in …
Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity
Obesity increases the risk of adverse outcomes during acute critical illnesses such as burns,
severe trauma, and acute pancreatitis. Although individuals with more body fat and higher …
severe trauma, and acute pancreatitis. Although individuals with more body fat and higher …
Glial origin of mesenchymal stem cells in a tooth model system
Mesenchymal stem cells occupy niches in stromal tissues where they provide sources of
cells for specialized mesenchymal derivatives during growth and repair 1 . The origins of …
cells for specialized mesenchymal derivatives during growth and repair 1 . The origins of …
ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity
Sialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers, including
breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-…
breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-…
Parasympathetic neurons originate from nerve-associated peripheral glial progenitors
The peripheral autonomic nervous system reaches far throughout the body and includes
neurons of diverse functions, such as sympathetic and parasympathetic. We show that the …
neurons of diverse functions, such as sympathetic and parasympathetic. We show that the …
Short-term mortality in acute pulmonary embolism: clot burden and signs of right heart dysfunction at CT pulmonary angiography
Purpose To assess the correlation between volumetric measurements of clot, semiquantitative
clot burden indexes, and signs of right heart dysfunction at computed tomographic (CT) …
clot burden indexes, and signs of right heart dysfunction at computed tomographic (CT) …