User profiles for Alessandro Pellegata

Alessandro F. Pellegata

- Verified email at ucl.ac.uk - Cited by 822

Alessandro Pellegata

- Verified email at unimi.it - Cited by 579

[HTML][HTML] Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

…, DHT Nguyen, G Li, R Schreiner, AF Pellegata… - Nature, 2020 - nature.com
Endothelial cells adopt tissue-specific characteristics to instruct organ development and
regeneration 1 , 2 . This adaptability is lost in cultured adult endothelial cells, which do not …

Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure

…, E Hirst, J König, AM Tedeschi, AF Pellegata… - Nature medicine, 2020 - nature.com
Intestinal failure, following extensive anatomical or functional loss of small intestine, has
debilitating long-term consequences for children 1 . The priority of patient care is to increase the …

[HTML][HTML] SARS-CoV-2 infection and replication in human gastric organoids

…, C Colantuono, L Di Filippo, AF Pellegata… - Nature …, 2021 - nature.com
COVID-19 typically manifests as a respiratory illness, but several clinical reports have described
gastrointestinal symptoms. This is particularly true in children in whom gastrointestinal …

[HTML][HTML] Detergent-enzymatic decellularization of swine blood vessels: insight on mechanical properties for vascular tissue engineering

AF Pellegata, M Asnaghi, I Stefani… - BioMed Research …, 2013 - hindawi.com
Small caliber vessels substitutes still remain an unmet clinical need; few autologous
substitutes are available, while synthetic grafts show insufficient patency in the long term. …

[HTML][HTML] Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors

…, P Maghsoudlou, CJ McCann, AF Pellegata… - Nature …, 2018 - nature.com
A tissue engineered oesophagus could overcome limitations associated with oesophageal
substitution. Combining decellularized scaffolds with patient-derived cells shows promise for …

[HTML][HTML] Whole organ tissue vascularization: engineering the tree to develop the fruits

AF Pellegata, AM Tedeschi, P De Coppi - Frontiers in bioengineering …, 2018 - frontiersin.org
Tissue engineering aims to regenerate and recapitulate a tissue or organ that has lost its
function. So far successful clinical translation has been limited to hollow organs in which …

Can corruption erode confidence in political institutions among European countries? Comparing the effects of different measures of perceived corruption

A Pellegata, V Memoli - Social Indicators Research, 2016 - Springer
The purpose of this study is to analyze the effects of corruption on institutional confidence
through testing alternative perceptions-based indexes of corruption. Scholars who have …

A cure worse than the disease? Exploring the health-economy trade-off during COVID-19

IE Oana, A Pellegata, C Wang - West european politics, 2021 - Taylor & Francis
Nationwide lockdowns implemented by governments to confront the COVID-19 pandemic
came at a high economic price. The article investigates citizens’ evaluation of the trade-off …

[HTML][HTML] Conjugated polymers mediate intracellular Ca2+ signals in circulating endothelial colony forming cells through the reactive oxygen species-dependent …

S Negri, P Faris, G Tullii, M Vismara, AF Pellegata… - Cell Calcium, 2022 - Elsevier
Endothelial colony forming cells (ECFCs) represent the most suitable cellular substrate to
induce revascularization of ischemic tissues. Recently, optical excitation of the light-sensitive …

Constraining political corruption: an empirical analysis of the impact of democracy

A Pellegata - Democratization, 2013 - Taylor & Francis
The present article addresses the relationship between democracy and political corruption.
Extending past studies, this article introduces important refinements that respond to …