User profiles for Alessandro Sette
Alessandro SetteVerified email at liai.org Cited by 130859 |
[PDF][PDF] Adaptive immunity to SARS-CoV-2 and COVID-19
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of antibodies), …
fundamental components of the adaptive immune system are B cells (the source of antibodies), …
[HTML][HTML] Pre-existing immunity to SARS-CoV-2: the knowns and unknowns
T cell reactivity against SARS-CoV-2 was observed in unexposed people; however, the source
and clinical relevance of the reactivity remains unknown. It is speculated that this reflects …
and clinical relevance of the reactivity remains unknown. It is speculated that this reflects …
The immune epitope database (IEDB): 2018 update
…, S Martini, JR Cantrell, DK Wheeler, A Sette… - Nucleic acids …, 2019 - academic.oup.com
The Immune Epitope Database (IEDB, iedb.org) captures experimental data confined in figures,
text and tables of the scientific literature, making it freely available and easily searchable …
text and tables of the scientific literature, making it freely available and easily searchable …
[PDF][PDF] Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals
Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development,
interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of pandemic …
interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of pandemic …
The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that first emerged in
late 2019 is responsible for a pandemic of severe respiratory illness. People infected with this …
late 2019 is responsible for a pandemic of severe respiratory illness. People infected with this …
[PDF][PDF] SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19
Over the past year, numerous studies in the peer reviewed and preprint literature have reported
on the virological, epidemiological and clinical characteristics of the coronavirus, SARS-…
on the virological, epidemiological and clinical characteristics of the coronavirus, SARS-…
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
INTRODUCTION Immunological memory is the basis for durable protective immunity after
infections or vaccinations. Duration of immunological memory after severe acute respiratory …
infections or vaccinations. Duration of immunological memory after severe acute respiratory …
Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines
Immunological memory is the basis of protective immunity provided by vaccines and previous
infections. Immunological memory can develop from multiple branches of the adaptive …
infections. Immunological memory can develop from multiple branches of the adaptive …
Nine major HLA class I supertypes account for the vast preponderance of HLA-A and-B polymorphism
Herein, we review the epitope approach to vaccine development, and discuss how knowledge
of HLA supertypes might be used as a tool in the development of such vaccines. After …
of HLA supertypes might be used as a tool in the development of such vaccines. After …
[PDF][PDF] Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity
Limited knowledge is available on the relationship between antigen-specific immune
responses and COVID-19 disease severity. We completed a combined examination of all three …
responses and COVID-19 disease severity. We completed a combined examination of all three …