The brain controls the heart directly through the sympathetic and parasympathetic branches
of the autonomic nervous system, which consists of multi-synaptic pathways from myocardial …

Sleep is characterized by coordinated cortical and cardiac oscillations reflecting communication
between the central (CNS) and autonomic (ANS) nervous systems. Here, we review …

There is increasing evidence that cardiovascular control during sleep is relevant for
cardiovascular risk. This evidence warrants increased experimental efforts to understand the …

The lack of noninvasive approaches to measure cardiac sympathetic nerve activity (CSNA)
has driven the development of indirect estimates such as the low-frequency (LF) power of …

Sleep is a heterogeneous behaviour. As a first approximation, it is subdivided objectively
into two states: non-rapid eye movement sleep (NREMS) and rapid eye movement sleep (…

Orexins (OX-A and OX-B), also referred to as hypocretin 1 and 2, are neuropeptides synthesized
by neurons located in the perifornical and lateral regions of the hypothalamus. Orexin …

Narcolepsy type 1 (NT1) is a lifelong disorder of sleep-wake dysregulation defined by clinical
symptoms, neurophysiological findings, and low hypocretin levels. Besides a role in sleep, …

Study Objectives: Although blood pressure during sleep and the difference in blood pressure
between sleep and wakefulness carry prognostic information, little is known on their central …

Cardiovascular disease (CVD) represents the first cause of death globally. The nighttime is
generally a period of relative protection from CVD events such as myocardial infarction, …

The central neural pathways underlying the physiological coordination between thermoregulation
and the controls of the wake-sleep behavior and cardiovascular function remain …