User profiles for Alessandro Sinigaglia

Alessandro Sinigaglia

Universita degli Studi di Padova
Verified email at unipd.it
Cited by 1972

[HTML][HTML] Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016

L Barzon, M Pacenti, A Berto, A Sinigaglia… - …, 2016 - eurosurveillance.org
We report the isolation of infectious Zika virus (ZIKV) in cell culture from the saliva of a patient
who developed a febrile illness after returning from the Dominican Republic to Italy, in …

[HTML][HTML] Antibody response to the BNT162b2 mRNA COVID-19 vaccine in subjects with prior SARS-CoV-2 infection

…, P Rodari, C Piubelli, S Caldrer, S Riccetti, A Sinigaglia… - Viruses, 2021 - mdpi.com
Although antibody levels progressively decrease following SARS-CoV-2 infection, the immune
memory persists for months. Thus, individuals who naturally contracted SARS-CoV-2 are …

[HTML][HTML] Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in∼ 40% of patients

…, O Neth, I Marín-Cruz, M Pacenti, A Sinigaglia… - Journal of Experimental …, 2023 - rupress.org
Mosquito-borne West Nile virus (WNV) infection is benign in most individuals but can cause
encephalitis in <1% of infected individuals. We show that ∼35% of patients hospitalized for …

[HTML][HTML] Detection of SARS-CoV-2 viral proteins and genomic sequences in human brainstem nuclei

…, L Barzon, M Sandre, E Carturan, A Sinigaglia… - npj Parkinson's …, 2023 - nature.com
Neurological manifestations are common in COVID-19, the disease caused by SARS-CoV-2.
Despite reports of SARS-CoV-2 detection in the brain and cerebrospinal fluid of COVID-19 …

[HTML][HTML] Differential plasmacytoid dendritic cell phenotype and type I Interferon response in asymptomatic and severe COVID-19 infection

…, S Fiore, D Ricci, M Iannetta, A Sinigaglia… - PLoS …, 2021 - journals.plos.org
SARS-CoV-2 fine-tunes the interferon (IFN)-induced antiviral responses, which play a key
role in preventing coronavirus disease 2019 (COVID-19) progression. Indeed, critically ill …

[HTML][HTML] Mycobacterium tuberculosis-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells

MP Etna, A Sinigaglia, A Grassi, E Giacomini… - PLoS …, 2018 - journals.plos.org
Autophagy is a primordial eukaryotic pathway, which provides the immune system with
multiple mechanisms for the elimination of invading pathogens including Mycobacterium …

[PDF][PDF] Zika virus: from pathogenesis to disease control

L Barzon, M Trevisan, A Sinigaglia… - FEMS microbiology …, 2016 - academic.oup.com
Zika virus is a mosquito-borne flavivirus discovered in Uganda in 1947. The virus has
emerged in recent years and spread in the Pacific Area and the Americas, where it has caused …

[HTML][HTML] Circulating microRNA signatures associated with disease severity and outcome in COVID-19 patients

A Giannella, S Riccetti, A Sinigaglia, C Piubelli… - Frontiers in …, 2022 - frontiersin.org
Background SARS-CoV-2 induces a spectrum of clinical conditions ranging from asymptomatic
infection to life threatening severe disease. Host microRNAs have been involved in the …

Autochthonous dengue outbreak in Italy 2020: clinical, virological and entomological findings

…, S Martini, S Riccetti, A Sinigaglia… - Journal of travel …, 2021 - academic.oup.com
Background In August 2020, in the context of COVID-19 pandemics, an autochthonous
dengue outbreak was identified for the first time in Italy. Methods Following the reporting of the …

[HTML][HTML] SARS-CoV-2 epitope mapping on microarrays highlights strong immune-response to N protein region

A Musicò, R Frigerio, A Mussida, L Barzon, A Sinigaglia… - Vaccines, 2021 - mdpi.com
A workflow for rapid SARS-CoV-2 epitope discovery on peptide microarrays is herein reported.
The process started with a proteome-wide screening of immunoreactivity based on the …