[PDF][PDF] Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions

GE Seabright, CA Cottrell, MJ van Gils, A D'addabbo… - Structure, 2020 - cell.com
Numerous broadly neutralizing antibodies (bnAbs) have been identified that target the
glycans of the HIV-1 envelope spike. Neutralization breadth is notable given that glycan …

[HTML][HTML] Impact of stabilizing mutations on the antigenic profile and glycosylation of membrane-expressed HIV-1 envelope glycoprotein

T Tong, A D'Addabbo, J Xu, H Chawla… - PLoS …, 2023 - journals.plos.org
Recent HIV-1 vaccine development has centered on “near native” soluble envelope glycoprotein
(Env) trimers that are artificially stabilized laterally (between protomers) and apically (…

[HTML][HTML] Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens

ET Crooks, F Almanza, A D'addabbo, E Duggan… - PLoS …, 2021 - journals.plos.org
HIV-1 vaccine immunofocusing strategies may be able to induce broadly-reactive neutralizing
antibodies (NAbs). Here, we engineered a panel of diverse, membrane-resident native HIV…

Impact of Glycan Depletion, Glycan Debranching and Increased Glycan Charge on HIV-1 Neutralization Sensitivity and Immunogenicity

A D'Addabbo, T Tong, E Crooks, K Osawa, J Xu… - bioRxiv, 2024 - biorxiv.org
Modifying HIV-1's envelope glycoprotein glycans can impact its neutralization sensitivity. The
use of the knock out cell line GnT1- prevents the elaboration of complex-type glycans, and …

Impact of Common Modifications on the Antigenic Profile and Glycosylation of Membrane-Expressed HIV-1 Envelope Glycoprotein.

T Tong, A D'Addabbo, J Xu, H Chawla, A Nguyen… - bioRxiv, 2023 - biorxiv.org
Recent HIV-1 vaccine development has centered on “near native” soluble envelope glycoprotein
(Env) trimers. These trimers are artificially stabilized laterally (between protomers) and …

Engineering glycosylation in HIV-1 vaccine design

A D'Addabbo - 2024 - eprints.soton.ac.uk
The development of a protective HIV-1 vaccine remains a major challenge to the scientific
community. The nature of the virus necessitates an immune response that is able to overcome …

Integrative characterization and phylogenetic relationships of Xiphinema rivesi and X. pachtaicum (Nematoda, Longidoridae) associated to vineyards in North Italy

…, V Papeschi, S Toninelli, T D'Addabbo… - European Journal of …, 2024 - Springer
The occurrence of Xiphinema species in the rhizosphere of vineyards showing general
decline phenotype in North Italy was investigated. Most of the collected soil samples contained …

[HTML][HTML] Results from the CUORE experiment

…, R Creswick, J Cushman, A D'Addabbo, D D'Aguanno… - Universe, 2019 - mdpi.com
The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric
experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton …

New results from the CUORE experiment

…, O Cremonesi, RJ Creswick, A D'Addabbo… - arXiv preprint arXiv …, 2020 - arxiv.org
The Cryogenic Underground Observatory for Rare Events (CUORE) is the first cryogenic
experiment searching for neutrinoless double-beta ($0\nu\beta\beta$) decay that has been able …

[PDF][PDF] Effectiveness of plant-derived formulations against the rootknot nematode Meloidogyne incognita (Kofoid et White) Chitw. in a protected tomato crop

G d'Errico, R Giacometti, O Soppelsa, M D'Alessio - Redia, 2011 - researchgate.net
… -D), the only one with primary nematicidal activity, and of most nematicides available on
the market, is increasing the need of new nematode control tools (LAMBERTI and DADDABBO, …