The objective of the study was to describe systemic bacterial infections occurring in acutely
ill and hospitalized children in a rural region in Ghana, regarding frequency, incidence, …

As human population density and antibiotic exposure increase, specialised bacterial
subtypes have begun to emerge. Arising among species that are common commensals and …

(TF) remains a problem of concern in many low-income countries. Salmonella enterica
serovar Typhi causes ≈ 22,000,000 symptomatic infections and 220,000 fatalities worldwide …

We compared the diagnostic accuracy of the Carba NP test with that of a straightforward
matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) …

Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases (ESBLs)
are among the most multidrug-resistant pathogens in hospitals and are spreading …

Background The diagnosis and antimicrobial treatment of pneumonia in African children in
the absence of diagnostic means such as x-ray facilities or microbiological laboratories relies …

The minimal concentration of antibiotic required to inhibit the growth of different isolates of a
given species with no acquired resistance mechanisms has a normal distribution. We have …

Background Plasmodium falciparum prevalence (PfPR) is a widely used metric for assessing
malaria transmission intensity. This study was carried out concurrently with the RTS,S/…

Malaria remains the single most frequent cause of death in Africa, killing one child every 30
s, but treatment decisions are often made only on clinical diagnosis, as laboratory …

Differentiation of infectious causes in severely ill children is essential but challenging in sub-
Saharan Africa. The aim of the study was to determine clinical indicators that are able to …