User profiles for Alex Finnegan

Alex Finnegan

- Verified email at illinois.edu - Cited by 346

Alexander Matthew David Finnegan

- Verified email at u.nus.edu - Cited by 63

[PDF][PDF] Transcriptional programming of normal and inflamed human epidermis at single-cell resolution

JB Cheng, AJ Sedgewick, AI Finnegan, P Harirchian… - Cell reports, 2018 - cell.com
Perturbations in the transcriptional programs specifying epidermal differentiation cause
diverse skin pathologies ranging from impaired barrier function to inflammatory skin disease. …

[HTML][HTML] Single-cell transcriptomics reveals spatial and temporal turnover of keratinocyte differentiation regulators

A Finnegan, RJ Cho, A Luu, P Harirchian, J Lee… - Frontiers in …, 2019 - frontiersin.org
Keratinocyte differentiation requires intricately coordinated spatiotemporal expression
changes that specify epidermis structure and function. This article utilizes single-cell RNA-seq …

[HTML][HTML] Maximum entropy methods for extracting the learned features of deep neural networks

A Finnegan, JS Song - PLoS computational biology, 2017 - journals.plos.org
New architectures of multilayer artificial neural networks and new methods for training them
are rapidly revolutionizing the application of machine learning in diverse fields, including …

Man-made natural and regenerated cellulosic fibres greatly outnumber microplastic fibres in the atmosphere

AMD Finnegan, R Süsserott, SE Gabbott… - Environmental …, 2022 - Elsevier
Atmospheric microplastics have been widely reported in studies around the world. Microfibres
are often the dominant morphology found by researchers, although synthetic (ie, plastic) …

[HTML][HTML] Projected plastic waste loss scenarios between 2000 and 2030 into the largest freshwater-lake system in Southeast Asia

AMD Finnegan, C Gouramanis - Scientific Reports, 2021 - nature.com
Freshwater plastic pollution is critically understudied in Southeast Asia (SEA). Recent modelling
studies indicate that SEA rivers contribute vast quantities of plastic to the world’s oceans…

[PDF][PDF] Epigenetic engineering of yeast reveals dynamic molecular adaptation to methylation stress and genetic modulators of specific DNMT3 family members

AI Finnegan, S Kim, H Jin, M Gapinske… - Nucleic acids …, 2020 - academic.oup.com
Cytosine methylation is a ubiquitous modification in mammalian DNA generated and maintained
by several DNA methyltransferases (DNMTs) with partially overlapping functions and …

A simple sample preparation method to significantly improve Fourier transform infrared (FT-IR) spectra of microplastics

A Finnegan, RC Süsserott, LH Koh… - Applied …, 2022 - journals.sagepub.com
Spectroscopic analysis has become an essential part of the rapidly growing field of
microplastic (MP) research. Here, we introduce a simple sample preparation method that …

First comparison of sampler surface areas for atmospheric microfibre deposition

AMD Finnegan, R Süsserott, LH Koh, WB Teo… - Environmental …, 2022 - Springer
Recent studies have reported on the widespread abundance of atmospheric microplastics (At-MPs)
and atmospheric anthropogenic microfibres (At-AMFs) in urban and remote locations…

A unified computational framework for modeling genome-wide nucleosome landscape

H Jin, AI Finnegan, JS Song - Physical biology, 2018 - iopscience.iop.org
Nucleosomes form the fundamental building blocks of eukaryotic chromatin, and previous
attempts to understand the principles governing their genome-wide distribution have spurred …

[PDF][PDF] Natural history societies in Victorian Scotland: Towards a historical geography of civic science

DA Finnegan - 2005 - academia.edu
This thesis examines the historical geography of Scottish natural history societies active
during the period 1831-1900. It argues that the work of the societies described and constituted …