Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic
peptide Aβ, degeneration of the cholinergic innervation to the hippocampus (the …

Although the neurogenesis-enhancing effects of exercise have been extensively studied,
the molecular mechanisms underlying this response remain unclear. Here, we propose that …

In the search for ways to combat degenerative neurological disorders, neurogenesis-stimulating
factors are proving to be a promising area of research. In this study, we show that the …

Prominin-1 (CD133) is commonly used to isolate stem and progenitor cells from the developing
and adult nervous system and to identify cancer stem cells in brain tumors. However, …

Erythropoiesis must be tightly balanced to guarantee adequate oxygen delivery to all tissues
in the body. This process relies predominantly on the hormone erythropoietin (EPO) and its …

Cellular redox states regulate the balance between stem cell maintenance and activation.
Increased levels of intracellular reactive oxygen species (ROS) are linked to proliferation and …

Here, we show that the lysophosphatidic acid receptor 1 (LPA 1 ) is expressed by a defined
population of type 1 stem cells and type 2a precursor cells in the adult mouse dentate gyrus. …

Accurate diagnosis of infection with the parasite Strongyloides stercoralis is hampered by the
low concentration of larvae in stool, rendering parasitological diagnosis insensitive. Even if …

Neurotrophins comprise a group of neuronal growth factors that are essential for the
development and maintenance of the nervous system. However, the immature pro-neurotrophins …

Parkinson’s disease (PD) is a chronic neurodegenerative disease that is characterised by a
loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. …