[HTML][HTML] Evidence for human lung stem cells

…, J Ferreira-Martins, A Matsuda… - … England Journal of …, 2011 - Mass Medical Soc
Background Although progenitor cells have been described in distinct anatomical regions of
the lung, description of resident stem cells has remained elusive. Methods Surgical lung-…

Cardiomyogenesis in the aging and failing human heart

…, J Ferreira-Martins, S Signore, F Sanada, A Matsuda… - 2012 - Am Heart Assoc
Background— Two opposite views of cardiac growth are currently held; one views the heart
as a static organ characterized by a large number of cardiomyocytes that are present at birth …

Cardiomyogenesis in the developing heart is regulated by c-kit–positive cardiac stem cells

J Ferreira-Martins, B Ogórek, D Cappetta, A Matsuda… - 2012 - Am Heart Assoc
… Joao Ferreira-Martins, Barbara Ogórek, Donato Cappetta, Alex Matsuda, Sergio Signore,
Domenico D’Amario, James Kostyla, Elisabeth Steadman, Noriko Ide-Iwata, Fumihiro …

[PDF][PDF] Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

…, T Fröhlich, M Hölscher, M Jedrysik, A Matsuda… - Cell Chemical …, 2022 - cell.com
The COVID-19 pandemic caused by SARS-CoV-2 has been socially and economically
devastating. Despite an unprecedented research effort and available vaccines, effective …

[PDF][PDF] Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity

A Czarna, J Plewka, L Kresik, A Matsuda, A Karim… - Structure, 2022 - cell.com
During RNA replication, coronaviruses require proofreading to maintain the integrity of their
large genomes. Nsp14 associates with viral polymerase complex to excise the mismatched …

Reduction in Kv current enhances the temporal dispersion of the action potential in diabetic myocytes: insights from a novel repolarization algorithm

…, A Cannata, Y Zhou, A Matsuda… - Journal of the …, 2016 - Am Heart Assoc
Background Diabetes is associated with prolongation of the QT interval of the electrocardiogram
and enhanced dispersion of ventricular repolarization, factors that, together with …

[HTML][HTML] DYRK1A Kinase inhibitors promote β-cell survival and insulin homeostasis

A Barzowska, B Pucelik, K Pustelny, A Matsuda… - Cells, 2021 - mdpi.com
The rising prevalence of diabetes is threatening global health. It is known not only for the
occurrence of severe complications but also for the SARS-Cov-2 pandemic, which shows that it …

[HTML][HTML] Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics

…, P Grygier, A Barzowska, B Pucelik, A Matsuda… - Scientific reports, 2023 - nature.com
The selective inhibition of kinases from the diabetic kinome is known to promote the
regeneration of beta cells and provide an opportunity for the curative treatment of diabetes. The …

Tracking chromatid segregation to identify human cardiac stem cells that regenerate extensively the infarcted myocardium

…, J Kim, C Arranto, F Sanada, D D'Amario, A Matsuda… - 2012 - Am Heart Assoc
… Jan Kajstura, Yingnan Bai, Donato Cappetta, Junghyun Kim, Christian Arranto, Fumihiro
Sanada, Domenico D’Amario, Alex Matsuda, Silvana Bardelli, Joao Ferreira-Martins, Toru …

Myocyte repolarization modulates myocardial function in aging dogs

…, R Kannappan, E Zhang, A Matsuda… - American Journal …, 2016 - journals.physiology.org
Studies of myocardial aging are complex and the mechanisms involved in the deterioration
of ventricular performance and decreased functional reserve of the old heart remain to be …