Ro52/Trim21 is targeted as an autoantigen in systemic lupus erythematosus and Sjögren's
syndrome. Polymorphisms in the Ro52 gene have been linked to these autoimmune …

We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …

Patients affected by Sjögren’s syndrome and systemic lupus erythematosus (SLE) carry
autoantibodies to an intracellular protein denoted Ro52. Although the serologic presence of …

In Sjögren's syndrome, like in most other autoimmune diseases, the enigma leading to a
pathogenic attack against self has not yet been solved. By definition, the disease must be …

Objective To investigate the role of the novel cytokine high mobility group box chromosomal
protein 1 (HMGB‐1) in the pathogenesis of cutaneous lupus erythematosus (CLE). Methods …

Circulating monocytes can compete for virtually any tissue macrophage niche and become
long-lived replacements that are phenotypically indistinguishable from their embryonic …

We identified a novel SARS-CoV-2 variant by viral whole-genome sequencing of 2,172
nasal/nasopharyngeal swab samples from 44 counties in California. Named B. 1.427/B. 1.429 to …

Ro52 is a member of the TRIM family of single-protein E3 ligases and is also a target for
autoantibody production in systemic lupus erythematosus and Sjögren's syndrome. We …

Interferon-α (IFN-α) has been implicated in the pathogenesis of Sjögren’s syndrome and
systemic lupus erythematosus. Ro52, which was recently identified as an E3 ligase with anti-…

Patients with systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS)
are typically characterized by the presence of autoantibodies and an IFN-signature. The …