User profiles for Alexander J Probst
Alexander J. ProbstFull Professor (W3), Research Alliance Ruhr, Faculty of Chemistry, University of Duisburg … Verified email at uni-due.de Cited by 17119 |
[HTML][HTML] Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system
The subterranean world hosts up to one-fifth of all biomass, including microbial communities
that drive transformations central to Earth’s biogeochemical cycles. However, little is known …
that drive transformations central to Earth’s biogeochemical cycles. However, little is known …
[HTML][HTML] A new view of the tree of life
The tree of life is one of the most important organizing principles in biology 1. Gene surveys
suggest the existence of an enormous number of branches 2, but even an approximation of …
suggest the existence of an enormous number of branches 2, but even an approximation of …
New CRISPR–Cas systems from uncultivated microbes
D Burstein, LB Harrington, SC Strutt, AJ Probst… - Nature, 2017 - nature.com
CRISPR–Cas systems provide microbes with adaptive immunity by employing short DNA
sequences, termed spacers, that guide Cas proteins to cleave foreign DNA 1 , 2 . Class 2 …
sequences, termed spacers, that guide Cas proteins to cleave foreign DNA 1 , 2 . Class 2 …
[HTML][HTML] Clades of huge phages from across Earth's ecosystems
Bacteriophages typically have small genomes 1 and depend on their bacterial hosts for
replication 2 . Here we sequenced DNA from diverse ecosystems and found hundreds of phage …
replication 2 . Here we sequenced DNA from diverse ecosystems and found hundreds of phage …
Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations
Candidate phyla radiation (CPR) bacteria and DPANN (an acronym of the names of the first
included phyla) archaea are massive radiations of organisms that are widely distributed …
included phyla) archaea are massive radiations of organisms that are widely distributed …
[HTML][HTML] Differential depth distribution of microbial function and putative symbionts through sediment-hosted aquifers in the deep terrestrial subsurface
An enormous diversity of previously unknown bacteria and archaea has been discovered
recently, yet their functional capacities and distributions in the terrestrial subsurface remain …
recently, yet their functional capacities and distributions in the terrestrial subsurface remain …
[HTML][HTML] Recovery of genomes from metagenomes via a dereplication, aggregation and scoring strategy
Microbial communities are critical to ecosystem function. A key objective of metagenomic
studies is to analyse organism-specific metabolic pathways and reconstruct community …
studies is to analyse organism-specific metabolic pathways and reconstruct community …
[PDF][PDF] Expansion of the global RNA virome reveals diverse clades of bacteriophages
High-throughput RNA sequencing offers broad opportunities to explore the Earth RNA
virome. Mining 5,150 diverse metatranscriptomes uncovered >2.5 million RNA virus contigs. …
virome. Mining 5,150 diverse metatranscriptomes uncovered >2.5 million RNA virus contigs. …
[HTML][HTML] SeqCode: a nomenclatural code for prokaryotes described from sequence data
Most prokaryotes are not available as pure cultures and therefore ineligible for naming under
the rules and recommendations of the International Code of Nomenclature of Prokaryotes (…
the rules and recommendations of the International Code of Nomenclature of Prokaryotes (…
[HTML][HTML] Roadmap for naming uncultivated Archaea and Bacteria
The assembly of single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs)
has led to a surge in genome-based discoveries of members affiliated with Archaea …
has led to a surge in genome-based discoveries of members affiliated with Archaea …