<p id="p001">Early-onset, severe retinal dystrophy caused by mutations in the gene encoding
retinal pigment epithelium–specific 65-kD protein (<italic>RPE65</italic>) is associated …

We have measured the inclusive b→ s γ branching ratio to be (2.32±0.57±0.35)× 10− 4,
where the first error is statistical and the second is systematic. Upper and lower limits on the …

The new detector for data recording by the CLEO collaboration at the Cornell Electron
Storage Ring is described. This detector has been designed to optimize studying e + e − …

Using the CLEO II detector, we have measured the differential cross sections for exclusive
two-photon production of light pseudoscalar mesons π 0, η, and η′. From our measurements …

The human MDR1 P-glycoprotein (Pgp) extrudes a variety of drugs across the plasma
membrane. The homologous MDR3 Pgp is required for phosphatidylcholine secretion into bile. …

We have observed the decays B 0→ K*(892) 0 γ and B−→ K*(892)− γ, which are evidence
for the quark-level process b→ sγ. The average branching fraction is (4.5±1.5±0.9)× 10− 5. …

The human multidrug-resistance protein (MRP) gene family contains at least six members:
MRP1, encoding the multidrug-resistance protein; MRP2 or cMOAT, encoding the canalicular …

Background Mutations in RPE65 cause Leber’s congenital amaurosis, a progressive retinal
degenerative disease that severely impairs sight in children. Gene therapy can result in …

Retroviral and lentiviral vector integration into host-cell chromosomes carries with it a finite
chance of causing insertional mutagenesis 1 . This risk has been highlighted by the induction …

Irreversible blindness caused by loss of photoreceptors may be amenable to cell therapy. We
previously demonstrated retinal repair 1 and restoration of vision through transplantation of …