The evolutionary origin of metazoan cell types such as neurons and muscles is not known.
Using whole-body single-cell RNA sequencing in a sponge, an animal without nervous …

Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …

Comparing single-cell transcriptomic atlases from diverse organisms can elucidate the origins
of cellular diversity and assist the annotation of new cell atlases. Yet, comparison between …

10.7554/eLife.48994.001 Single-cell RNA sequencing has spurred the development of
computational methods that enable researchers to classify cell types, delineate developmental …

Schistosomes are parasitic flatworms causing one of the most prevalent infectious diseases
from which millions of people are currently suffering. These parasites have high fecundity …

Nanomedicine approaches have the potential to transform the battle against parasitic worm (helminth)
infections, a major global health scourge from which billions are currently suffering…

Recent advances in single-cell sequencing provide a unique opportunity to gain novel insights
into the diversity, lineage, and functions of cell types constituting a tissue/organ. Here, we …

Schistosomes cause one of the most devastating neglected tropical diseases, schistosomiasis.
Their transmission is accomplished through a complex life cycle with two obligate hosts …

Like humans, insects rely on precise regulation of their internal environments to survive. The
insect renal system consists of Malpighian tubules and nephrocytes that share similarities to …

Schistosomes are parasitic flatworms causing one of the most prevalent infectious diseases
from which millions of people are currently suffering. Their germline outputs many fertilized …