[HTML][HTML] BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

U Sahin, A Muik, I Vogler, E Derhovanessian, LM Kranz… - Nature, 2021 - nature.com
BNT162b2, a nucleoside-modified mRNA formulated in lipid nanoparticles that encodes the
SARS-CoV-2 spike glycoprotein (S) stabilized in its prefusion conformation, has …

Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera

A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl… - Science, 2022 - science.org
The globally circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant of concern Omicron (B.1.1.529) has a large number of mutations, especially in the spike …

Neutralization of SARS-CoV-2 lineage B. 1.1. 7 pseudovirus by BNT162b2 vaccine–elicited human sera

A Muik, AK Wallisch, B Sänger, KA Swanson, J Mühl… - Science, 2021 - science.org
Recently, a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage
called B.1.1.7 (variant of concern: VOC 202012/01), which is reported to spread more …

Omicron BA. 2 breakthrough infection enhances cross-neutralization of BA. 2.12. 1 and BA. 4/BA. 5

A Muik, BG Lui, M Bacher, AK Wallisch, A Toker… - Science …, 2022 - science.org
BNT162b2-vaccinated individuals after Omicron BA.1 breakthrough infection have strong
serum-neutralizing activity against Omicron BA.1, BA.2, and previous SARS-CoV-2 variants of …

[HTML][HTML] COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

U Sahin, A Muik, E Derhovanessian, I Vogler, LM Kranz… - Nature, 2020 - nature.com
An effective vaccine is needed to halt the spread of the severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) pandemic. Recently, we reported safety, tolerability and …

[HTML][HTML] Neutralizing activity of BNT162b2-elicited serum

…, M Cutler, D Cooper, SC Weaver, A Muik… - … England Journal of …, 2021 - Mass Medical Soc
Variant SARS-CoV-2 and BNT162b2 Vaccine How well do serum samples obtained from
persons injected with the BNT162b2 vaccine neutralize the P.1, B.1.1.7, and B.1.135 lineages …

[HTML][HTML] BNT162b vaccines protect rhesus macaques from SARS-CoV-2

AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik… - Nature, 2021 - nature.com
A safe and effective vaccine against COVID-19 is urgently needed in quantities that are
sufficient to immunize large populations. Here we report the preclinical development of two …

[HTML][HTML] BNT162b2-elicited neutralization of B. 1.617 and other SARS-CoV-2 variants

…, KA Swanson, H Cai, M Cutler, D Cooper, A Muik… - Nature, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuing to evolve
around the world, generating new variants that are of concern on the basis of their potential for …

[HTML][HTML] Neutralization of ba. 4–ba. 5, ba. 4.6, ba. 2.75. 2, bq. 1.1, and xbb. 1 with bivalent vaccine

…, D Cooper, Q Yang, H Cai, A Muik… - … England Journal of …, 2023 - Mass Medical Soc
Neutralization of BA.4–BA.5, BA.4.6, BA.2.75.2, BQ.1.1, and XBB.1 with Bivalent Vaccine |
NEJM Skip to main content NEJM Group Follow Us Facebook Twitter Instagram YouTube …

Omicron BA. 1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes

J Quandt, A Muik, N Salisch, BG Lui, S Lutz… - Science …, 2022 - science.org
Omicron is the evolutionarily most distinct severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant of concern (VOC) to date. We report that Omicron BA.1 breakthrough …