Purpose Whole-exome and whole-genome sequencing have transformed the discovery of
genetic variants that cause human Mendelian disease, but discriminating pathogenic from …

Background: Dilated cardiomyopathy (DCM) is genetically heterogeneous, with >100
purported disease genes tested in clinical laboratories. However, many genes were originally …

Background Variants in the cardiomyocyte-specific RNA splicing factor RBM20 have been
linked to familial cardiomyopathy, but the causative genetic architecture and clinical …

Objective To investigate the association between retinopathy and chronic kidney disease.
Methods In this observational, cross-sectional study, 2605 patients of the Chronic Renal …

Clusters of tumor cells are often observed in the blood of cancer patients. These structures
have been described as malignant entities for more than 50 years, although their …

And for those historical legacies perpetuated through contemporary social relations penetrating
and infusing a double consciousness of social life, not just for Black folk, but that duality …

… The deep breathing test and Valsalva maneuvers were also … radioisotope count observed
during DUF was not due to loss … to plasma during DUF, increasing the plasma counts slightly. …

… For example, during sepsis, platelet aggregation was impaired depending on sepsis severity
in a number of studies [30-32], although platelet adhesion was preserved [33]. P-selectin se…

… To examine the effect of booster vaccination, we tested neutralization of Victoria, Delta,
and Omicron viruses using sera from individuals receiving 3 doses of ADZ1222 (n = 41) or …

Antibodies are crucial to immune protection against SARS-CoV-2, with some in emergency
use as therapeutics. Here, we identify 377 human monoclonal antibodies (mAbs) …