User profiles for Alexander van der Bourg

Alexander van der Bourg

Brain Research Institute, University of Zurich
Verified email at hifo.uzh.ch
Cited by 1408

[PDF][PDF] Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance

…, AS Chuong, NC Klapoetke, L Li, A Van Der Bourg… - Neuron, 2015 - cell.com
An increasingly powerful approach for studying brain circuits relies on targeting genetically
encoded sensors and effectors to specific cell types. However, current approaches for this …

The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue

…, R Kastli, M Schaettin, L Egolf, A Van Der Bourg… - Nature …, 2019 - nature.com
Light-sheet microscopy is an ideal technique for imaging large cleared samples; however,
the community is still lacking instruments capable of producing volumetric images of …

Layer-specific refinement of sensory coding in developing mouse barrel cortex

A van der Bourg, JW Yang, V Reyes-Puerta… - Cerebral …, 2017 - academic.oup.com
Rodent rhythmic whisking behavior matures during a critical period around 2 weeks after
birth. The functional adaptations of neocortical circuitry during this developmental period …

Multiphoton in vivo imaging with a femtosecond semiconductor disk laser

…, SM Link, S Carta, A van der Bourg… - Biomedical optics …, 2017 - opg.optica.org
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several
applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped …

[HTML][HTML] A model of human neural networks reveals NPTX2 pathology in ALS and FTLD

…, B Gatta, M Panatta, A van der Bourg… - Nature, 2024 - nature.com
Human cellular models of neurodegeneration require reproducibility and longevity, which is
necessary for simulating age-dependent diseases. Such systems are particularly needed for …

Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

…, V Hoop, I Delvendahl, M Panatta, A van der Bourg… - bioRxiv, 2021 - biorxiv.org
Human cellular models of neurodegeneration require reproducibility and longevity, which is
necessary for simulating these age-dependent diseases. Such systems are particularly …

[HTML][HTML] Developmental divergence of sensory stimulus representation in cortical interneurons

R Kastli, R Vighagen, A van der Bourg… - Nature …, 2020 - nature.com
Vasocative-intestinal-peptide (VIP + ) and somatostatin (SST + ) interneurons are involved
in modulating barrel cortex activity and perception during active whisking. Here we identify a …

Nogo-A deletion increases the plasticity of the optokinetic response and changes retinal projection organization in the adult mouse visual system

A Guzik-Kornacka, A van der Bourg, F Vajda… - Brain Structure and …, 2016 - Springer
The inhibitory action of Nogo-A on axonal growth has been well described. However, much
less is known about the effects that Nogo-A could exert on the plasticity of neuronal circuits …

Temporal refinement of sensory‐evoked activity across layers in developing mouse barrel cortex

A van der Bourg, JW Yang, MC Stüttgen… - European Journal of …, 2019 - Wiley Online Library
… mouse barrel cortex - van der Bourg - 2019 - European Journal of Neuroscience - Wiley Online
Library … Alexander van der Bourg and Jenq-Wei Yang are considered as co-first authors. …

[PDF][PDF] Functional maturation of sensory coding in developing mouse barrel cortex

A van der Bourg - 2016 - zora.uzh.ch
Touch perception is an essential sensory modality enabling organisms to interact with their
world. The study of sensory integration and perception are essential for the understanding of …