Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice

…, AE Qualls, AB Flemington… - … of Physiology-Cell …, 2020 - journals.physiology.org
The objective of this study was to interrogate the link between mitochondrial dysfunction and
mitochondrial-specific autophagy in skeletal muscle. C57BL/6J mice were used to establish …

[HTML][HTML] Metabolism, Oxidative Stress and Cell Signaling: Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice

…, KF Tehrani, AE Qualls, AB Flemington… - American Journal of …, 2020 - ncbi.nlm.nih.gov
The objective of this study was to interrogate the link between mitochondrial dysfunction and
mitochondrial-specific autophagy in skeletal muscle. C57BL/6J mice were used to establish …

Mitochondrial dysfunction and autophagy responses to skeletal muscle stress

AS Nichenko, WM Southern, AE Qualls, AB Flemington… - bioRxiv, 2019 - biorxiv.org
Autophagy plays an important role in mitochondrial maintenance, yet many details of skeletal
muscle autophagic activity are unresolved in the context of muscle stress and/or damage. …

[PDF][PDF] Reducing recycling collection costs through training

A Hogan, B Flemington - RESOURCE RECYCLING, 1996 - p2infohouse.org
Alexandra Hogan works in the Training Division of the Toronto offlce of Resource Integration
Systems Ltd. Bob Flemington … can be reached at (416) 594-3456, or by E-mail at flemington

[HTML][HTML] Salt-inducible kinase 1 is a potential therapeutic target in desmoplastic small round cell tumor

…, K Moroz, DH Drewry, ME Burow, E Flemington… - Oncogenesis, 2022 - nature.com
Desmoplastic Small Round Cell Tumor (DSRCT) is a rare and aggressive malignant cancer
caused by a chromosomal translocation t(11;22)(p13;q12) that produces an oncogenic …

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

…, M Escudero, E Flemington… - Proceedings of the …, 2003 - National Acad Sciences
Oxidative stress is believed to be an important mediator of neurodegeneration. However,
the transcriptional pathways induced in neurons by oxidative stress that activate protective …

Structure-guided design of highly selective and potent covalent inhibitors of ERK1/2

…, G Fairley, L Feron, V Flemington… - Journal of medicinal …, 2015 - ACS Publications
The RAS/RAF/MEK/ERK signaling pathway has been targeted with a number of small
molecule inhibitors in oncology clinical development across multiple disease indications. …

[HTML][HTML] Development of isotope-enriched phosphatidylinositol-4-and 5-phosphate cellular mass spectrometry probes

AM Joffrin, AM Saunders, D Barneda, V Flemington… - Chemical …, 2021 - pubs.rsc.org
Synthetic phosphatidylinositol phosphate (PtdInsPn) derivatives play a pivotal role in broadening
our understanding of PtdInsPn metabolism. However, the development of such tools is …

Assessing the responses of aquatic macrophytes to the application of a lanthanum modified bentonite clay, at Loch Flemington, Scotland, UK

IDM Gunn, S Meis, SC Maberly, BM Spears - Hydrobiologia, 2014 - Springer
… Loch Flemington is a shallow lake of international … Loch Flemington is still classified as being
in ‘unfavourable … to the future management of Loch Flemington and in the wider context of …

B Alert: Hepatitis B virus infection in children in V ictoria

G Jimenez, G Alex, G Paxton… - … of Paediatrics and …, 2013 - Wiley Online Library
Aim The aim of this study is to determine the demographic, clinical and serological patterns
of hepatitis B in children in V ictoria over a 17‐year period. Methods Retrospective analysis …