The level of controllability has been shown to modulate the effects of stress on physiology
and behavior. In the present study, we investigated the effects of controllable vs. …

BACKGROUND:: Mitochondria have been suggested to be involved in the pathology of
bipolar disorder (BD) and schizophrenia. However, the mechanism underlying mitochondrial …

The basolateral amygdala (BLA) has been repeatedly shown to mediate the effects of stress
on memory‐related processes. However, the way in which stress influences BLA itself has …

Stress‐sensitive psychopathologies such as post‐traumatic stress disorder are characterized
by deficits in fear extinction and dysfunction of corticolimbic circuits mediating extinction. …

Electrical stimulation of the rodent medial prefrontal cortex (mPFC), including the infralimbic
cortex (IL), immediately prior to or during fear extinction training facilitates extinction memory…

Stressors differ in their physiological and behavioral outcomes. One of the major mechanisms
by which stressors affect the brain and behavior is alteration in neuronal plasticity. We …

In recent years precision fMRI has emerged in human brain research, demonstrating
characterization of individual differences in brain organization. However, mechanistic investigations …

Children with the autosomal dominant single gene disorder, neurofibromatosis type 1 (NF1),
display multiple structural and functional changes in the central nervous system, resulting in …

Dysfunction in corticolimbic circuits that mediate the extinction of learned fear responses is
thought to underlie the perseveration of fear in stress-related psychopathologies, including …

We have recently described an A350V mutation in IQSEC2 associated with intellectual
disability, autism and epilepsy. We sought to understand the molecular pathophysiology of this …