Combining theory, model, and experiment to explain how intrinsic theta rhythms are generated in an in vitro whole hippocampus preparation without oscillatory inputs
KA Ferguson, AP Chatzikalymniou, FK Skinner - eneuro, 2017 - eneuro.org
Scientists have observed local field potential theta rhythms (3–12 Hz) in the hippocampus for
decades, but understanding the mechanisms underlying their generation is complicated by …
decades, but understanding the mechanisms underlying their generation is complicated by …
Deciphering the contribution of oriens-lacunosum/moleculare (OLM) cells to intrinsic θ rhythms using biophysical local field potential (LFP) models
AP Chatzikalymniou, FK Skinner - Eneuro, 2018 - eneuro.org
Oscillations in local field potentials (LFPs) are prevalent and contribute to brain function. An
understanding of the cellular correlates and pathways affecting LFPs is needed, but many …
understanding of the cellular correlates and pathways affecting LFPs is needed, but many …
[HTML][HTML] A hypothesis for theta rhythm frequency control in CA1 microcircuits
…, AR Lunyov, J Lefebvre, AP Chatzikalymniou - Frontiers in neural …, 2021 - frontiersin.org
Computational models of neural circuits with varying levels of biophysical detail have been
generated in pursuit of an underlying mechanism explaining the ubiquitous hippocampal …
generated in pursuit of an underlying mechanism explaining the ubiquitous hippocampal …
Linking minimal and detailed models of CA1 microcircuits reveals how theta rhythms emerge and how their frequencies are controlled
The wide variety of cell types and their inherent biophysical complexities pose a challenge to
our understanding of oscillatory activities produced by cellular-based computational models…
our understanding of oscillatory activities produced by cellular-based computational models…
Cholecystokinin-expressing (CCK+) basket cells are key controllers of theta-gamma coupled rhythms in the hippocampus
AP Chatzikalymniou, S Sengupta, J Lefebvre… - bioRxiv, 2022 - biorxiv.org
It has been shown that different inhibitory cell types underlie brain rhythmic and cross-frequency
coupling output, but exactly how inhibitory cell types manifest their contributions to these …
coupling output, but exactly how inhibitory cell types manifest their contributions to these …
Linking minimal and detailed models of CA1 microcircuits reveals how theta rhythms emerge and their frequencies controlled
AP Chatzikalymniou, M Gumus, FK Skinner - Hippocampus, 2021 - Wiley Online Library
The wide variety of cell types and their biophysical complexities pose a challenge in our
ability to understand oscillatory activities produced by cellular‐based computational network …
ability to understand oscillatory activities produced by cellular‐based computational network …
Oscillatory Dynamics of Brain Microcircuits: Modeling Perspectives and Neurological Disease Considerations
FK Skinner, AP Chatzikalymniou - Computational Models of …, 2017 - Wiley Online Library
We describe two previously presented approaches to modeling oscillations in brain microcircuits
in which multiple levels of organization and cellular perspectives are considered. We …
in which multiple levels of organization and cellular perspectives are considered. We …
Combining theory, model and experiment to understand how theta rhythms are generated in the hippocampus
KA Ferguson, AP Chatzikalymniou, FK Skinner - bioRxiv, 2017 - biorxiv.org
Scientists have observed theta rhythms (3–12 Hz) in the hippocampus for decades, but we
do not have a clear understanding of how they are generated. This is largely due to the …
do not have a clear understanding of how they are generated. This is largely due to the …
Towards a general framework for modeling large-scale biophysical neuronal networks: a full-scale computational model of the rat dentate gyrus
…, C Schneider, D Hadjiabadi, A Chatzikalymniou… - bioRxiv, 2021 - biorxiv.org
Large-scale computational models of the brain are necessary to accurately represent
anatomical and functional variability in neuronal biophysics across brain regions and also to …
anatomical and functional variability in neuronal biophysics across brain regions and also to …
[BOOK][B] On the generation of theta rhythms in the hippocampus
A Chatzikalymniou - 2021 - search.proquest.com
A prevalent local field potential (LFP) rhythm in the CA1 hippocampus associated with
memory processing and spatial navigation is the (3-12 Hz) theta oscillation. Theta rhythms …
memory processing and spatial navigation is the (3-12 Hz) theta oscillation. Theta rhythms …