A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes
A well-balanced human diet includes a significant intake of non-starch polysaccharides,
collectively termed ‘dietary fibre’, from the cell walls of diverse fruits and vegetables 1 . Owing to …
collectively termed ‘dietary fibre’, from the cell walls of diverse fruits and vegetables 1 . Owing to …
[HTML][HTML] Sucrose and invertases, a part of the plant defense response to the biotic stresses
AS Tauzin, T Giardina - Frontiers in plant science, 2014 - frontiersin.org
Sucrose is the main form of assimilated carbon which is produced during photosynthesis and
then transported from source to sink tissues via the phloem. This disaccharide is known to …
then transported from source to sink tissues via the phloem. This disaccharide is known to …
The devil lies in the details: how variations in polysaccharide fine-structure impact the physiology and evolution of gut microbes
EC Martens, AG Kelly, AS Tauzin, H Brumer - Journal of molecular biology, 2014 - Elsevier
The critical importance of gastrointestinal microbes to digestion of dietary fiber in humans
and other mammals has been appreciated for decades. Symbiotic microorganisms expand …
and other mammals has been appreciated for decades. Symbiotic microorganisms expand …
Molecular dissection of xyloglucan recognition in a prominent human gut symbiont
AS Tauzin, KJ Kwiatkowski, NI Orlovsky, CJ Smith… - MBio, 2016 - Am Soc Microbiol
Polysaccharide utilization loci (PUL) within the genomes of resident human gut Bacteroidetes
are central to the metabolism of the otherwise indigestible complex carbohydrates known …
are central to the metabolism of the otherwise indigestible complex carbohydrates known …
[PDF][PDF] A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses
A Tauzin, M Nayrac, M Benlarbi, SY Gong, R Gasser… - Cell host & …, 2021 - cell.com
While the standard regimen of the BNT162b2 mRNA vaccine for SARS-CoV-2 includes two
doses administered 3 weeks apart, some public health authorities are spacing these doses, …
doses administered 3 weeks apart, some public health authorities are spacing these doses, …
[HTML][HTML] T cell apoptosis characterizes severe Covid-19 disease
…, C Gotti, M Leclercq, A Nicolas, A Tauzin… - Cell Death & …, 2022 - nature.com
Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms involved
are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized that …
are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized that …
[PDF][PDF] Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy
…, S Ding, R Gasser, C Fink, Y Chen, A Tauzin… - Immunity, 2021 - cell.com
Neutralizing antibodies (NAbs) are effective in treating COVID-19, but the mechanism of
immune protection is not fully understood. Here, we applied live bioluminescence imaging (BLI) …
immune protection is not fully understood. Here, we applied live bioluminescence imaging (BLI) …
[PDF][PDF] A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
…, K Symmes, S Ding, M Benlarbi, SY Gong, A Tauzin… - Cell reports, 2022 - cell.com
Emerging evidence indicates that both neutralizing and Fc-mediated effector functions of
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …
[PDF][PDF] Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses
A Tauzin, SY Gong, G Beaudoin-Bussières, D Vézina… - Cell host & …, 2022 - cell.com
The standard regimen of the BNT162b2 mRNA vaccine for SARS-CoV-2 includes two doses
administered three weeks apart. However, some public health authorities spaced these …
administered three weeks apart. However, some public health authorities spaced these …
[PDF][PDF] Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
Emerging variants of concern for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
can transmit more efficiently and partially evade protective immune responses, …
can transmit more efficiently and partially evade protective immune responses, …