User profiles for Alexandre Baccouche
Alexandre BaccoucheCNRS researcher, IEMN, University of Lille Verified email at univ-lille.fr Cited by 356 |
Nonlinear decision-making with enzymatic neural networks
Artificial neural networks have revolutionized electronic computing. Similarly, molecular
networks with neuromorphic architectures may enable molecular decision-making on a level …
networks with neuromorphic architectures may enable molecular decision-making on a level …
Dynamic DNA-toolbox reaction circuits: A walkthrough
A Baccouche, K Montagne, A Padirac, T Fujii… - Methods, 2014 - Elsevier
In living organisms, the integration of signals from the environment and the molecular
computing leading to a cellular response are orchestrated by Gene Regulatory Networks (GRN). …
computing leading to a cellular response are orchestrated by Gene Regulatory Networks (GRN). …
Massively parallel and multiparameter titration of biochemical assays with droplet microfluidics
A Baccouche, S Okumura, R Sieskind, E Henry… - Nature …, 2017 - nature.com
Biochemical systems in which multiple components take part in a given reaction are of
increasing interest. Because the interactions between these different components are complex …
increasing interest. Because the interactions between these different components are complex …
Functional analysis of single enzymes combining programmable molecular circuits with droplet-based microfluidics
…, R Espada, A Dramé-Maigné, A Baccouche… - Nature …, 2024 - nature.com
The analysis of proteins at the single-molecule level reveals heterogeneous behaviours that
are masked in ensemble-averaged techniques. The digital quantification of enzymes …
are masked in ensemble-averaged techniques. The digital quantification of enzymes …
Silicon chambers for enhanced incubation and imaging of microfluidic droplets
Droplet microfluidics has become a powerful tool in life sciences, underlying digital assays,
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …
Model atmospheric aerosols convert to vesicles upon entry into aqueous solution
S Nader, A Baccouche, F Connolly… - ACS Earth and Space …, 2022 - ACS Publications
Aerosols are abundant on the Earth and likely played a role in prebiotic chemistry. Aerosol
particles coagulate, divide, and sample a wide variety of conditions conducive to synthesis. …
particles coagulate, divide, and sample a wide variety of conditions conducive to synthesis. …
[HTML][HTML] Morphological Manipulation of DNA Gel Microbeads with Biomolecular Stimuli
…, S Benner, Y Torii, Y Tanabe, K Takada, A Baccouche… - Nanomaterials, 2021 - mdpi.com
Hydrogels are essential in many fields ranging from tissue engineering and drug delivery to
food sciences or cosmetics. Hydrogels that respond to specific biomolecular stimuli such as …
food sciences or cosmetics. Hydrogels that respond to specific biomolecular stimuli such as …
Silicon as a microfluidic material for imaging and incubation of droplets
Droplet microfluidics has become a powerful tool in life sciences, underlying digital assays,
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …
Toggling Between Two Limit Cycles in a Molecular Ecosystem
A Fauste-Gay, N Lobato-Dauzier, A Baccouche… - New Generation …, 2022 - Springer
In this article, we introduce an oscillatory molecular system with two independent limit cycles,
dependent on initial conditions. The system is composed of two crossed Predator-Prey …
dependent on initial conditions. The system is composed of two crossed Predator-Prey …
License to cut: Smart RNA guides for conditional control of CRISPR-Cas9
The Cas9 enzyme is a programmable endonuclease, whose target sequence is directed by
a companion RNA guide. Cas9 and RNA guides have revolutionized biology, enabling facile …
a companion RNA guide. Cas9 and RNA guides have revolutionized biology, enabling facile …