In pharmaceutical research, high‐content screening is an integral part of lead candidate
development. Measuring drug response in vitro by examining over 40 parameters, including …

Mass cytometry (MC) is a high throughput multiparameter analytical technique for determining
biomarker expression in cells. In MC, antibodies (Abs) are tagged with heavy metal …

Mass cytometry (MC) is a bioanalytical technique that uses metal-tagged antibodies (Abs) for
high-dimensional single-cell immunoassays. Currently, this technology can measure over …

We employ imaging mass cytometry (IMC) to investigate in vitro uptake and cellular distribution
of DNA-functionalized gold nanoparticles (AuNPs). IMC enables the multiparametric …

We are interested in developing lanthanide nanoparticles (NPs) as high sensitivity tagging
reagents for antibodies to analyze cells by mass cytometry (MC). Two key prerequisites for …

The synthesis of a polylysine polymer functionalized with the previously reported astonishingly
inert [In(cb-te2pa)] + chelate was performed. A biotin end group allowed the conjugation …

Mass cytometry is a highly multiplexed single-cell analysis platform that uses metal-tagged
reagents to identify multiple cellular biomarkers. The current metal-tagged reagent …

Mass cytometry is a novel cell-by-cell analysis technique, which uses elemental tags instead
of fluorophores. Sample cells undergo rapid ionization in inductively coupled plasma and …

Results of in vitro drug testing are correlated with clinical response to chemotherapy: Accuracy
to predict clinical drug resistance was found to be as high as 90%. The benefit of using in …

Background High-parameter flow cytometry is a major tool used in human and mouse
studies to discover novel immunological mechanisms of infectious diseases, cancer and …