[HTML][HTML] Defective excitatory/inhibitory synaptic balance and increased neuron apoptosis in a zebrafish model of dravet syndrome
A Brenet, R Hassan-Abdi, J Somkhit, C Yanicostas… - Cells, 2019 - mdpi.com
Dravet syndrome is a type of severe childhood epilepsy that responds poorly to current anti-epileptic
drugs. In recent years, zebrafish disease models with Scn1Lab sodium channel …
drugs. In recent years, zebrafish disease models with Scn1Lab sodium channel …
Bixafen, a succinate dehydrogenase inhibitor fungicide, causes microcephaly and motor neuron axon defects during development
A Brenet, R Hassan-Abdi, N Soussi-Yanicostas - Chemosphere, 2021 - Elsevier
Succinate dehydrogenase inhibitors (SDHIs), the most widely used fungicides in agriculture
today, act by blocking succinate dehydrogenase (SDH), an essential and evolutionarily …
today, act by blocking succinate dehydrogenase (SDH), an essential and evolutionarily …
[HTML][HTML] Neurons expressing pathological tau protein trigger dramatic changes in microglial morphology and dynamics
R Hassan-Abdi, A Brenet, M Bennis… - Frontiers in …, 2019 - frontiersin.org
Microglial cells, the resident macrophages of the brain, are important players in the
pathological process of numerous neurodegenerative disorders, including tauopathies, a …
pathological process of numerous neurodegenerative disorders, including tauopathies, a …
[HTML][HTML] Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal …
A Brenet, J Somkhit, R Hassan-Abdi, C Yanicostas… - Scientific Reports, 2020 - nature.com
With millions of intoxications each year and over 200,000 deaths, organophosphorus (OP)
compounds are an important public health issue worldwide. OP poisoning induces …
compounds are an important public health issue worldwide. OP poisoning induces …
[HTML][HTML] Microglia mitigate neuronal activation in a zebrafish model of Dravet syndrome
It has been known for a long time that epileptic seizures provoke brain neuroinflammation
involving the activation of microglial cells. However, the role of these cells in this disease …
involving the activation of microglial cells. However, the role of these cells in this disease …
A fast, simple, and affordable technique to measure oxygen consumption in living zebrafish embryos
J Somkhit, R Loyant, A Brenet, R Hassan-Abdi… - Zebrafish, 2020 - liebertpub.com
In all animal species, oxygen consumption is a key process that is partially impaired in a
large number of pathological situations and thus provides informative details on the …
large number of pathological situations and thus provides informative details on the …
Contribution à l'étude des conséquences de l'épilepsie sur le développement cérébral et l'activité des cellules microgliales
A Brenet - 2021 - hal.science
L'épilepsie est une maladie neurologique qui touche plus de 50 millions de personnes dans
le monde. Elle se caractérise par des crises récurrentes dues à la surexcitation synchrone …
le monde. Elle se caractérise par des crises récurrentes dues à la surexcitation synchrone …
Preclinical zebrafish model for organophosphorus intoxication: neuronal hyperexcitation, behavioral abnormalities and subsequent brain damages
A Brenet, J Somkhit, R Hassan-Abdi, C Yanicostas… - bioRxiv, 2019 - biorxiv.org
As key compounds for modern cultivation practices, organophosphorus (OP)-containing
pesticides have become an important public health and environmental issues, worldwide, …
pesticides have become an important public health and environmental issues, worldwide, …
Bixafen, a succinate dehydrogenase inhibitor fungicide, causes microcephaly and motor neuron axon defects during development
R Hassan-Abdi, A Brenet, N Soussi-Yanicostas - bioRxiv, 2020 - biorxiv.org
Succinate dehydrogenase inhibitors (SDHIs) are the most widely used fungicides against
plant parasitic fungi. They act by blocking the enzyme succinate dehydrogenase (SDH), a key …
plant parasitic fungi. They act by blocking the enzyme succinate dehydrogenase (SDH), a key …
Neurons expressing pathological Tau protein trigger dramatic noninflammatory changes in microglial morphology and dynamics
Microglial cells, the resident macrophages of the brain, are important players in the
pathological process of numerous neurodegenerative disorders, including tauopathies, a …
pathological process of numerous neurodegenerative disorders, including tauopathies, a …