User profiles for Alexandre Colato

Alexandre Colato

Professor of Physics, Universidade Federal de São Carlos
Verified email at ufscar.br
Cited by 244

Complete genetic linkage can subvert natural selection

PJ Gerrish, A Colato, AS Perelson… - Proceedings of the …, 2007 - National Acad Sciences
The intricate adjustment of organisms to their environment demonstrates the effectiveness of
natural selection. But Darwin himself recognized that certain biological features could limit …

Genomic mutation rates that neutralize adaptive evolution and natural selection

PJ Gerrish, A Colato… - Journal of The Royal …, 2013 - royalsocietypublishing.org
When mutation rates are low, natural selection remains effective, and increasing the mutation
rate can give rise to an increase in adaptation rate. When mutation rates are high to begin …

How unequal vaccine distribution promotes the evolution of vaccine escape

PJ Gerrish, F Saldana, B Galeota-Sprung, A Colato… - medRxiv, 2021 - medrxiv.org
In the context of the ongoing SARS-CoV-2 pandemic, health officials warn that vaccines must
be uniformly distributed within and among countries if we are to quell the pandemic. Yet …

Effect of selection on the topology of genealogical trees

LP Maia, A Colato, JF Fontanari - Journal of theoretical biology, 2004 - Elsevier
Selection is one of the factors that most influence the shape of genealogical trees. Here we
report results of simulations of the infinite-sites version of Moran's model of population …

Effects of random migration in population dynamics

A Colato, SS Mizrahi - Physical Review E, 2001 - APS
We study the influence of random migration of a species (may be insects) in the population
dynamics when initially all the individuals live in a primordial site (their habitats may be trees)…

[PDF][PDF] Natural selection promotes the evolution of recombination 2: during the selective process

…, F Cordero, B Galeota-Sprung, A Colato… - Physical Review E In …, 2021 - scholar.archive.org
The ubiquity of genetic mixing in nature has eluded unified explanation since the time of
Darwin. Conditions that promote the evolution of genetic mixing (recombination) are fairly well …

Natural selection and the advantage of recombination

…, B Galeota-Sprung, F Cordero, P Sniegowski, A Colato… - bioRxiv, 2020 - biorxiv.org
Exchanging genetic material with another individual seems risky from an evolutionary stand-point,
and yet living things across all scales and phyla do so quite regularly. The …

Lineage dynamics and mutation–selection balance in non-adapting asexual populations

S Pénisson, PD Sniegowski, A Colato… - Journal of Statistical …, 2013 - iopscience.iop.org
In classical population genetics, mutation–selection balance refers to the equilibrium frequency
of a deleterious allele established and maintained under two opposing forces: recurrent …

Periodical cicadas: A minimal automaton model

GO Cardozo, D de AMM Silvestre, A Colato - Physica A: Statistical …, 2007 - Elsevier
The Magicicada spp. life cycles with its prime periods and highly synchronized emergence
have defied reasonable scientific explanation since its discovery. During the last decade …

Pandemic response: Isolationism or solidarity?: An evolutionary perspective

PJ Gerrish, F Saldaña, A Colato, EER Torres… - … , Simulations, and AI for …, 2023 - Elsevier
Health officials have stressed the importance of a more uniform distribution of SARS-CoV-2
vaccines within and among countries, yet there has been little critical assessment of the …