Quantum Hall systems are characterized by quantization of the Hall conductance—a bulk
property rooted in the topological structure of the underlying quantum states 1 . In condensed …

Fluoropyrimidines (FU) are still the most prescribed anticancer drugs for the treatment of solid
cancers. However, fluoropyrimidines cause severe toxicities in 10 to 40% of patients and …

The first layer of plant immunity is activated by cell surface receptor‐like kinases (RLKs) and
proteins (RLPs) that detect infectious pathogens. Constitutive interaction with the …

… Joseph Ciccolini, Laetitia Dahan, Nicolas André, Alexandre Evrard, Muriel Duluc, Aurore
Blesius, Chenguang Yang, Sarah Giacometti, Caroline Brunet, Caroline Raynal, Adrien Ortiz …

So far little is known on the functional role of phosphorylation in the heat stress response of
plants. Here we present evidence that heat stress activates the Arabidopsis mitogen-…

Background Deficiency in dihydropyrimidine dehydrogenase (DPD) enzyme is the main
cause of severe and lethal fluoropyrimidine-related toxicity. Various approaches have been …

Background Clinical efficacy of chemotherapy in colorectal cancer is subjected to broad inter-individual
variations leading to the inability to predict outcome and toxicity. The …

Dihydropyrimidine dehydrogenase (DPD) deficiency leads to dramatic overexposure to
fluorouracil (5-FU), resulting in a potentially lethal outcome in patients treated with standard …

Coherent superposition states of a mesoscopic quantum object play a major role in our
understanding of the quantum to classical boundary, as well as in quantum-enhanced metrology …

Objectives Low first-dose peak serum concentrations of amikacin and gentamicin are commonly
reported in ICU patients. The present study aimed to assess whether 30 mg/kg amikacin …