User profiles for Alexandre Kabla

Alexandre Kabla

University of Cambridge
Verified email at cam.ac.uk
Cited by 6198

Fracture in living tissues

A Bonfanti, J Duque, A Kabla, G Charras - Trends in Cell Biology, 2022 - cell.com
During development and in adult physiology, living tissues are continuously subjected to
mechanical stresses originating either from cellular processes intrinsic to the tissue or from …

The role of single-cell mechanical behaviour and polarity in driving collective cell migration

…, T Chen, ML Heuzé, P Marcq, RM Mège, AJ Kabla… - Nature physics, 2020 - nature.com
The directed migration of cell collectives is essential in various physiological processes, such
as epiboly, intestinal epithelial turnover, and convergent extension during morphogenesis, …

Tissue tectonics: morphogenetic strain rates, cell shape change and intercalation

GB Blanchard, AJ Kabla, NL Schultz, LC Butler… - Nature …, 2009 - nature.com
The dynamic reshaping of tissues during morphogenesis results from a combination of
individual cell behaviors and collective cell rearrangements. However, a comprehensive …

[HTML][HTML] Strain-induced alignment in collagen gels

D Vader, A Kabla, D Weitz, L Mahadevan - PloS one, 2009 - journals.plos.org
Collagen is the most abundant extracellular-network-forming protein in animal biology and
is important in both natural and artificial tissues, where it serves as a material of great …

Emerging modes of collective cell migration induced by geometrical constraints

…, TL Lai, P Hersen, AJ Kabla… - Proceedings of the …, 2012 - National Acad Sciences
The role of geometrical confinement on collective cell migration has been recognized but has
not been elucidated yet. Here, we show that the geometrical properties of the environment …

[HTML][HTML] Fractional viscoelastic models for power-law materials

A Bonfanti, JL Kaplan, G Charras, A Kabla - Soft Matter, 2020 - pubs.rsc.org
Soft materials often exhibit a distinctive power-law viscoelastic response arising from broad
distribution of time-scales present in their complex internal structure. A promising tool to …

Characterizing the mechanics of cultured cell monolayers

…, L Peter, J Bellis, B Baum, AJ Kabla… - Proceedings of the …, 2012 - National Acad Sciences
One-cell-thick monolayers are the simplest tissues in multicellular organisms, yet they fulfill
critical roles in development and normal physiology. In early development, embryonic …

Collective cell migration: leadership, invasion and segregation

AJ Kabla - Journal of The Royal Society Interface, 2012 - royalsocietypublishing.org
A number of biological processes, such as embryo development, cancer metastasis or wound
healing, rely on cells moving in concert. The mechanisms leading to the emergence of …

Guidance of collective cell migration by substrate geometry

…, MC Leong, H Hirata, NS Gov, AJ Kabla… - Integrative …, 2013 - academic.oup.com
Collective behavior refers to the emergence of complex migration patterns over scales
larger than those of the individual elements constituting a system. It plays a pivotal role in …

Cell shape changes indicate a role for extrinsic tensile forces in Drosophila germ-band extension

LC Butler, GB Blanchard, AJ Kabla, NJ Lawrence… - Nature cell …, 2009 - nature.com
Drosophila germ-band extension (GBE) is an example of the convergence and extension
movements that elongate and narrow embryonic tissues. To understand the collective cell …