The combination of high-throughput sequencing and in vivo crosslinking approaches leads
to the progressive uncovering of the complex interdependence between cellular …

Specific elements of viral genomes regulate interactions within host cells. Here, we calculated
the secondary structure content of >2000 coronaviruses and computed >100 000 human …

To the Editor: Long noncoding RNAs (lncRNAs, which comprise 68% of the human transcriptome
with average length of 1,000 nt) interact with various RNA-binding proteins (RBPs) to …

The long non-coding RNA Xist induces heterochromatinization of the X chromosome by
recruiting repressive protein complexes to chromatin. Here we gather evidence, from the …

Cells must coordinate the activation of thousands of replication origins dispersed throughout
their genome. Active transcription is known to favor the formation of mammalian origins, …

Synchronization of mitochondrial and cytoplasmic translation rates is critical for the
maintenance of cellular fitness, with cancer cells being especially vulnerable to translational …

Prediction of protein–RNA interactions is important to understand post-transcriptional events
taking place in the cell. Here we introduce catRAPID omics v2.0, an update of our web …

Long Interspersed Nuclear Elements-1s (L1s) are transposable elements that constitute
most of the genome’s transcriptional output yet have still largely unknown functions. Here we …

Protein–RNA interactions are implicated in a number of physiological roles as well as
diseases, with molecular mechanisms ranging from defects in RNA splicing, localization and …

Proteins and RNAs assemble in membrane-less organelles that organize intracellular spaces
and regulate biochemical reactions. The ability of proteins and RNAs to form condensates …