User profiles for Alexei A. Koulakov

Alexei Koulakov

Cold Spring Harbor Laboratory
Verified email at cshl.edu
Cited by 6055

Maps in the brain: what can we learn from them?

DB Chklovskii, AA Koulakov - Annu. Rev. Neurosci., 2004 - annualreviews.org
▪ Abstract In mammalian visual cortex, neurons are organized according to their functional
properties into multiple maps such as retinotopic, ocular dominance, orientation preference, …

Precise olfactory responses tile the sniff cycle

R Shusterman, MC Smear, AA Koulakov… - Nature …, 2011 - nature.com
In terrestrial vertebrates, sniffing controls odorant access to receptors, and therefore sets the
timescale of olfactory stimuli. We found that odorants evoked precisely sniff-locked activity in …

Model for a robust neural integrator

AA Koulakov, S Raghavachari, A Kepecs… - Nature …, 2002 - nature.com
Integrator circuits in the brain show persistent firing that reflects the sum of previous excitatory
and inhibitory inputs from external sources. Integrator circuits have been implicated in …

[PDF][PDF] Orbitofrontal cortex is required for optimal waiting based on decision confidence

A Lak, GM Costa, E Romberg, AA Koulakov, ZF Mainen… - Neuron, 2014 - cell.com
Confidence judgments are a central example of metacognition—knowledge about one's
own cognitive processes. According to this metacognitive view, confidence reports are …

[PDF][PDF] Orientation preference patterns in mammalian visual cortex: a wire length minimization approach

AA Koulakov, DB Chklovskii - Neuron, 2001 - cell.com
In the visual cortex of many mammals, orientation preference changes smoothly along the
cortical surface, with the exception of singularities such as pinwheels and fractures. The …

[HTML][HTML] A primacy code for odor identity

CD Wilson, GO Serrano, AA Koulakov… - Nature …, 2017 - nature.com
Humans can identify visual objects independently of view angle and lighting, words
independently of volume and pitch, and smells independently of concentration. The computational …

High-throughput sequencing of single neuron projections reveals spatial organization in the olfactory cortex

…, Y Li, MB Davis, JM Kebschull, AM Zador, AA Koulakov… - Cell, 2022 - cell.com
In most sensory modalities, neuronal connectivity reflects behaviorally relevant stimulus
features, such as spatial location, orientation, and sound frequency. By contrast, the prevailing …

[PDF][PDF] Sparse incomplete representations: a potential role of olfactory granule cells

AA Koulakov, D Rinberg - Neuron, 2011 - cell.com
Mitral/tufted cells of the olfactory bulb receive odorant information from receptor neurons and
transmit this information to the cortex. Studies in awake behaving animals have found that …

Correlated connectivity and the distribution of firing rates in the neocortex

AA Koulakov, T Hromádka, AM Zador - Journal of Neuroscience, 2009 - Soc Neuroscience
Two recent experimental observations pose a challenge to many cortical models. First, the
activity in the auditory cortex is sparse, and firing rates can be described by a lognormal …

Competition is a driving force in topographic mapping

…, AM Litke, A Sher, AA Koulakov… - Proceedings of the …, 2011 - National Acad Sciences
Topographic maps are the primary means of relaying spatial information in the brain.
Understanding the mechanisms by which they form has been a goal of experimental and …