There is accumulating evidence that platelets play roles beyond their traditional functions in
thrombosis and hemostasis, eg, in inflammatory processes, infection and cancer, and that …

Introduction Defects of platelet functional responses in COVID-19 were reported, but their
origin and pathophysiological significance are unclear. The objective of this study was to …

Although reversible platelet aggregation observed in response to ADP stimulation in the
presence of calcium is a well-known phenomenon, its mechanisms are not entirely clear. To …

Platelets are blood cells responsible for vascular integrity preservation. The activation of
platelet receptor C-type lectin-like receptor II-type (CLEC-2) could partially mediate the latter …

Immune thrombocytopenia (ITP) is an autoimmune condition primarily induced by the loss
of immune tolerance to the platelet glycoproteins. Here we develop a novel flow cytometry …

Immune thrombocytopenia (ITP) is believed to be associated with platelet function defects.
However, their mechanisms are poorly understood, in particular with regard to differences …

Platelets are anucleate blood cells with reported roles in hemostasis and immune responses,
which possess a functional receptor for bacterial lipopolysaccharides (LPSs), the well-…

Background Platelet-type bleeding disorder 20 (BDPLT20), as known as SLFN14-related
thrombocytopenia, is a rare inherited thrombocytopenia (IT). Previously, only 5 heterozygous …

Background Platelets are blood cells responsible for the prevention of blood loss upon
vessel wall disruption. It has been demonstrated that platelet functioning differs significantly …

Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor of infancy that is
commonly associated with a life-threatening thrombocytopenic condition, Kasabach-Merritt …