[HTML][HTML] DNAJB9 is a specific immunohistochemical marker for fibrillary glomerulonephritis

…, ME Fidler, S Kaaki, N Quellard, A Rinsant… - Kidney international …, 2018 - Elsevier
Introduction Fibrillary glomerulonephritis (FGN) is a rare disease with unknown pathogenesis
and a poor prognosis. Until now, the diagnosis of this disease has required demonstration …

Immunoglobulin light-chain toxicity in a mouse model of monoclonal immunoglobulin light-chain deposition disease

…, C Carrion, C Oblet, A Rinsant… - Blood, The Journal …, 2020 - ashpublications.org
Light chain (LC) deposition disease (LCDD) is a rare disorder characterized by glomerular
and peritubular amorphous deposits of a monoclonal immunoglobulin LC, leading to nodular …

Heavy chain fibrillary glomerulonephritis: a case report

…, F Bridoux, V Javaugue, S Bender, A Rinsant… - American Journal of …, 2019 - Elsevier
Heavy chain amyloidosis and heavy chain deposition disease are the only known kidney
diseases caused by the deposition of truncated immunoglobulin heavy chains. Fibrillary …

[HTML][HTML] Randall-Type Monoclonal IgE Kappa Light-Heavy Chain Deposition Disease

P Isnard, N Benichou, D Sibon, A Rinsant… - Kidney International …, 2023 - Elsevier
Results A 65-year-old woman was referred to our nephrology department for renal impairment
and low-grade proteinuria. Her past medical history consisted of hypertension and IgE …

Acquired cutis laxa from heavy chain deposition disease

V Gillion, MC Vekemans, A Rinsant… - Kidney …, 2022 - kidney-international.org
A35-year-old woman presented with fatigue, nausea, marked lower-limb edema, and
hypertension (180/100 mm Hg). Blood tests showed kidney failure (serum creatinine: 10 mg/dl), …

Glomerulosclerosis and kidney failure in a mouse model of monoclonal immunoglobulin light-chain deposition disease

…, A Bonaud, V Javaugue, C Carrion, C Oblet, A Rinsant… - bioRxiv, 2019 - biorxiv.org
Light chain deposition disease (LCDD) is a rare disorder characterized by glomerular and
peritubular amorphous deposits of a monoclonal immunoglobulin (Ig) light chain (LC), leading …

[HTML][HTML] Light chain only variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits is associated with a high detection rate of the pathogenic …

SH Nasr, CP Larsen, C Sirac, JD Theis, C Domenger… - Kidney international, 2020 - Elsevier
IgG (mainly IgG3) is the most commonly involved isotype in proliferative glomerulonephritis
with monoclonal immunoglobulin deposits (PGNMID). Here we describe the first series of …

[HTML][HTML] Cytokines in endocrine dysfunction of plasma cell disorders

E Feigerlová, SF Battaglia-Hsu - Mediators of inflammation, 2017 - hindawi.com
Monoclonal gammopathies (MG) are classically associated with lytic bone lesions,
hypercalcemia, anemia, and renal insufficiency. However, in some cases, symptoms of endocrine …

RNA-based immunoglobulin repertoire sequencing is a new tool for the management of monoclonal gammopathy of renal (kidney) significance

V Javaugue, V Pascal, S Bender, S Nasraddine… - Kidney International, 2022 - Elsevier
… 3 , Mathilde Dargelos 1 9 , Mehdi Alizadeh 4 , Alexis Saintamand 5 , Matthieu Filloux 3 ,
Paco … Rinsant and A. Lehericy for their technical assistance and E. Guerin of the sequencing …

Mouse models to study plasma cells and monoclonal immunoglobulin-related diseases

MV Ayala - 2020 - theses.hal.science
Abnormal plasma cells (PC) proliferation is frequent (approximately 5% of people over 50)
but in most cases remains asymptomatic, detected by the presence of a monoclonal …