Sumoylation is an essential post-translational modification that is catalysed by a small number
of modifying enzymes but regulates thousands of target proteins in a dynamic manner. …

Small ubiquitin-like modifiers (SUMOs) are essential for the regulation of several cellular
processes and are potential therapeutic targets owing to their involvement in diseases such as …

Protein conjugation with Small ubiquitin-like modifier (SUMOylation) has critical roles during
cell cycle progression. Many important cell cycle regulators, including many oncogenes and …

SUMOylation is a reversible post-translational modification essential for genome stability.
Using high-resolution MS, we have studied global SUMOylation in human cells in a site-…

The small ubiquitin-like modifier (SUMO) family in vertebrates includes three different family
members that are conjugated as post-translational modifications to target proteins. SUMO-2 …

The length and precise linkage of polyubiquitin chains is important for their biological activity.
Although other ubiquitin-like proteins have the potential to form polymeric chains their …

Reversible protein modification by small ubiquitin-like modifiers (SUMOs) is critical for eukaryotic
life. Mass spectrometry-based proteomics has proven effective at identifying hundreds …

Small ubiquitin-like modifiers (SUMOs) are post-translational modifications (PTMs) that regulate
nuclear cellular processes. Here we used an augmented K0–SUMO proteomics strategy …

The response to DNA double-strand breaks (DSBs) requires alterations in chromatin
structure to promote the assembly of repair complexes on broken chromosomes. Non-homologous …

The SUMO family in vertebrates includes at least three distinct proteins (SUMO-1, -2, and -3)
that are added as post-translational modifications to target proteins. A considerable number …