To investigate the molecular mechanisms through which Epstein-Barr virus (EBV) may
contribute to Systemic Lupus Erythematosus (SLE) pathogenesis, we interrogated SLE genetic …

Glioblastoma and gliomas can have a wide range of histopathologic subtypes. These
heterogeneous histologic phenotypes originate from tumor cells with the distinct functions of …

Background Genome wide association studies have identified > 200 susceptibility loci
accounting for much of the heritability of multiple sclerosis (MS). Epstein-Barr virus (EBV), a …

Translating the findings of genome wide association studies (GWAS) to new therapies requires
identification of the relevant immunological contexts to interrogate for genetic effects. In …

Here we developed KARAJ, a fast and flexible Linux command-line tool to automate the end-to-end
process of querying and downloading a wide range of genomic and transcriptomic …

Although the causes of Multiple Sclerosis (MS) still remain largely unknown, multiple lines of
evidence suggest that Epstein–Barr virus (EBV) infection may contribute to the development …

Recent advances in medical image analysis have been made to improve our understanding
of how disease develops, behaves, and responds to treatment. Magnetic resonance …

Within tumors, chemokines and their cognate receptors are expressed by infiltrated leukocytes,
cancerous cells, and related cells of stroma, like tumor-associated fibroblasts and tumor-…

In recent decades, considerable efforts have been made to understand the mechanism of
memory, cognition, and relevant neurodegenerative diseases in the human brain. Several …

Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease, characterised
by the demyelination of neurons in the central nervous system. Whilst it is unclear what …