In the developing central nervous system, oligodendrocyte precursor cells (OPCs) differentiate
into oligodendrocytes, which form myelin around axons. Oligodendrocytes and myelin are …

Embryonic neural stem cells (NSCs, ie, radial glia) in the ventricular-subventricular zone (V-SVZ)
generate the majority of neurons and glia in the forebrain. Postnatally, embryonic radial …

Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility
to the disease. Known susceptibility genes account for less than 25% of the familial risk of …

Nutritional requirements for vitamin D during pregnancy have been inadequately described,
and there are conflicting data on the impact of gestation on vitamin D status. In the present …

Objectives This study aimed to quantify the value of reducing chimeric antigen receptor T-cell
(CAR-T) treatment wait times on patients with refractory and relapsed aggressive blood …

Two potential breast cancer susceptibility genes, encoding the BRCA1‐interacting proteins
ZNF350 (or ZBRK1) and BRIP1 (or BACH1), have been identified in yeast two‐hybrid screens…

Target-focused (often described as “rational”) drug discovery starts with the identification and
validation of one or more target biomolecules whose modulation will interfere with disease …

Cheminformatics is the chemical field that deals with the storage, retrieval, analysis and
manipulation of an increasing volume of available chemical data, and it plays a fundamental role …

… Voting was computed as formerly described by Zhang and Muegge [39]. AUC ROCs were
computed with the pROC package [40] and Delong’s method was applied for the statistical …

We previously showed that the anti-fungal drug ciclopirox olamine effectively inhibits
replication of herpes simplex virus (HSV)-1 and HSV-2. Given the rise of HSV strains that are …