The exosome is a major eukaryotic nuclease located in both the nucleus and the cytoplasm
that contributes to the processing, quality control and/or turnover of a large number of …

The exosome is a complex involved in the maturation of rRNA and sn-snoRNA, in the degradation
of short-lived noncoding RNAs, and in the quality control of RNAs produced in mutants…

Ribosome biogenesis in eukaryotes depends on the coordinated action of ribosomal and
nonribosomal proteins that guide the assembly of preribosomal particles. These intermediate …

Intracellular pathogens such as Listeria monocytogenes subvert cellular functions through
the interaction of bacterial effectors with host components. Here we found that a secreted …

Allelic forms of DRG1/AFG2 confer resistance to the drug diazaborine, an inhibitor of ribosome
biogenesis in Saccharomyces cerevisiae. Our results show that the AAA-ATPase Drg1 is …

Bacterial infections trigger the expression of type I and II interferon genes but little is known
about their effect on type III interferon (IFN-λ) genes, whose products play important roles in …

Gene expression regulation is a critical question in host-pathogen interactions, and RNAs act
as key players in this process. In this review, we focus on the mammalian RNA response to …

Listeria monocytogenes is a food-borne pathogen causing an opportunistic disease called
listeriosis. This bacterium invades and replicates in most cell types, due to its multiple …

Eukaryotic pre-ribosomes go through cytoplasmic maturation steps before entering
translation. The nucleocytoplasmic proteins participating in these late stages of maturation are …

The intestinal tract is the largest reservoir of microbes in the human body. The intestinal
microbiota is thought to be able to modulate alterations of the gut induced by enteropathogens, …