User profiles for Alice Shaam Al Abed

A. Shaam Al Abed

Australian National University
Verified email at anu.edu.au
Cited by 208

[HTML][HTML] Preventing and treating PTSD-like memory by trauma contextualization

AS Al Abed, EG Ducourneau, C Bouarab… - Nature …, 2020 - nature.com
Post-traumatic stress disorder (PTSD) is characterized by emotional hypermnesia on which
preclinical studies focus so far. While this hypermnesia relates to salient traumatic cues, …

Temporal memory and its enhancement by estradiol requires surface dynamics of hippocampal CA1 N-methyl-D-aspartate receptors

…, L Ladépêche, V Lamothe, AS Al Abed… - Biological …, 2016 - Elsevier
Background Identifying the underlying cellular mechanisms of episodic memory is an important
challenge, since this memory, based on temporal and contextual associations among …

Temporal binding function of dorsal CA1 is critical for declarative memory formation

A Sellami, AS Al Abed… - Proceedings of the …, 2017 - National Acad Sciences
Temporal binding, the process that enables association between discontiguous stimuli in
memory, and relational organization, a process that enables the flexibility of declarative …

Er81 transcription factor fine-tunes striatal cholinergic interneuron activity and drives habit formation

…, Y Ranjbar-Slamloo, AS Al Abed… - Journal of …, 2021 - Soc Neuroscience
The molecular mechanisms tuning cholinergic interneuron (CIN) activity, although crucial
for striatal function and behavior, remain largely unexplored. Previous studies report that the …

Age‐related impairment of declarative memory: linking memorization of temporal associations to GluN2B redistribution in dorsal CA1

AS Al Abed, A Sellami, M Potier, EG Ducourneau… - Aging …, 2020 - Wiley Online Library
GluN2B subunits of NMDA receptors have been proposed as a target for treating age‐related
memory decline. They are indeed considered as crucial for hippocampal synaptic plasticity …

[PDF][PDF] Vangl2 in the dentate network modulates pattern separation and pattern completion

…, A Quiedeville, M Garret, B Atchama, AS Al Abed… - Cell Reports, 2020 - cell.com
The organization of spatial information, including pattern completion and pattern separation
processes, relies on the hippocampal circuits, yet the molecular and cellular mechanisms …

Parvalbumin Interneuron Activity in Autism Underlies Susceptibility to PTSD-like Memory Formation

AS Al Abed, TV Allen, NY Ahmed, A Sellami, Y Sontani… - iScience, 2024 - cell.com
A rising concern in Autism Spectrum Disorder (ASD) is the heightened sensitivity to trauma,
the potential consequences of which have been overlooked, particularly upon the severity of …

Estradiol enhances retention but not organization of hippocampus-dependent memory in intact male mice

AS Al Abed, A Sellami, L Brayda-Bruno… - …, 2016 - Elsevier
Because estrogens have mostly been studied in gonadectomized females, effects of chronic
exposure to environmental estrogens in the general population are underestimated. …

Derivatization-free LC-MS/MS method for estrogen quantification in mouse brain highlights a local metabolic regulation after oral versus subcutaneous administration

E Lozan, S Shinkaruk, SA Al Abed, V Lamothe… - Analytical and …, 2017 - Springer
17β-Estradiol (17β-E 2 ) is a steroid with pleiotropic actions. In addition to being a sexual
hormone, it is also produced in the brain where it modulates the reproductive axis. It has been …

To deliberate, remember; to anticipate, forget: Cognitive deliberation profiles underpinning active forgetting-dependent everyday-like memory performance in young …

C Stevens, AS Al Abed, A Sellami, EG Ducourneau… - bioRxiv, 2023 - biorxiv.org
… While increase of ITI has classically been understood to increase the demand on memory
retention (Al Abed et al., 2016), in the present study we nuance this understanding by …