[HTML][HTML] Rotavirus calcium dysregulation manifests as dynamic calcium signaling in the cytoplasm and endoplasmic reticulum
AL Chang-Graham, JL Perry, AC Strtak… - Scientific Reports, 2019 - nature.com
Like many viruses, rotavirus (RV) dysregulates calcium homeostasis by elevating cytosolic
calcium ([Ca 2+ ]cyt) and decreasing endoplasmic reticulum (ER) stores. While an overall, …
calcium ([Ca 2+ ]cyt) and decreasing endoplasmic reticulum (ER) stores. While an overall, …
Rotavirus induces intercellular calcium waves through ADP signaling
INTRODUCTION Rotavirus (RV) causes severe diarrheal disease in children worldwide by
broadly dysregulating intestinal homeostasis. The mechanisms of RV diarrhea are …
broadly dysregulating intestinal homeostasis. The mechanisms of RV diarrhea are …
Recovirus NS1-2 has viroporin activity that induces aberrant cellular calcium signaling to facilitate virus replication
AC Strtak, JL Perry, MN Sharp, AL Chang-Graham… - Msphere, 2019 - Am Soc Microbiol
Enteric viruses in the Caliciviridae family cause acute gastroenteritis in humans and animals,
but the cellular processes needed for virus replication and disease remain unknown. A …
but the cellular processes needed for virus replication and disease remain unknown. A …
Dysregulation of Endogenous and Paracrine Calcium Signaling Pathways by Rotaviruses and Caliciviruses
…, KA Engevik, MA Engevik, AC Strtak… - The FASEB …, 2020 - Wiley Online Library
Despite causing severe, potentially life‐threatening diarrhea, most enteric viruses only
infect a small percent of intestinal epithelial cells. Thus, the induction of paracrine signaling …
infect a small percent of intestinal epithelial cells. Thus, the induction of paracrine signaling …
Receptor-operated cation entry—more than esoteric terminology?
T Gudermann, M Mederos y Schnitzler, A Dietrich - Science's STKE, 2004 - science.org
Many hormones and neurotransmitters elicit an increase in the intracellular calcium
concentration by binding to phospholipase C–linked G protein–coupled receptors. Activated …
concentration by binding to phospholipase C–linked G protein–coupled receptors. Activated …
[PDF][PDF] The origin of diarrhea in rotavirus infection
M egan Stanifer, S Boulant - researchgate.net
After rotavirus infection, nonstructural protein 4 (NSP4) induces intracellular Ca2+ waves that
mediate the release of adenosine diphosphate (ADP). ADP activates purinergic receptors …
mediate the release of adenosine diphosphate (ADP). ADP activates purinergic receptors …
Secondary denervation is a chronic pathophysiologic sequela of volumetric muscle loss
JR Sorensen, DB Hoffman… - Journal of Applied …, 2021 - journals.physiology.org
… Alicia Strtak for assistance with depth and 3-D reconstruction images and Trevor Johnson
for assistance in completion of this work. This work was completed using the TissueScope LE …
for assistance in completion of this work. This work was completed using the TissueScope LE …