A mitochondria-specific mutational signature of aging: increased rate of A> G substitutions on the heavy strand
AG Mikhailova, AA Mikhailova, K Ushakova… - Nucleic acids …, 2022 - academic.oup.com
The mutational spectrum of the mitochondrial DNA (mtDNA) does not resemble any of the
known mutational signatures of the nuclear genome and variation in mtDNA mutational …
known mutational signatures of the nuclear genome and variation in mtDNA mutational …
Genomic signatures of eusocial evolution in insects
AA Mikhailova, S Rinke, MC Harrison - Current Opinion in Insect Science, 2023 - Elsevier
Highlights Comparative genomics can uncover molecular signatures of eusocial evolution.
Changes in transcriptional regulation with each emergence of eusociality. Evolution of …
Changes in transcriptional regulation with each emergence of eusociality. Evolution of …
Major changes in domain arrangements are associated with the evolution of termites
AA Mikhailova, E Dohmen… - Journal of Evolutionary …, 2024 - academic.oup.com
Abstract Domains as functional protein units and their rearrangements along the phylogeny
can shed light on the functional changes of proteomes associated with the evolution of …
can shed light on the functional changes of proteomes associated with the evolution of …
[PDF][PDF] Live-bearing cockroach genome reveals convergent evolutionary mechanisms linked to viviparity in insects and beyond
Live birth (viviparity) has arisen repeatedly and independently among animals. We sequenced
the genome and transcriptome of the viviparous Pacific beetle-mimic cockroach and …
the genome and transcriptome of the viviparous Pacific beetle-mimic cockroach and …
[PDF][PDF] Unravelling the Mitochondrial Mutational Landscape in Chordates: damage-induced versus replication-induced signatures, their Etiologies, and dynamics
To elucidate the primary factors shaping mitochondrial DNA (mtDNA) mutagenesis, we
reconstructed a deep 192-component mtDNA mutational spectrum using 129,100 polymorphic …
reconstructed a deep 192-component mtDNA mutational spectrum using 129,100 polymorphic …
A mitochondrial mutational signature of temperature in ectothermic and endothermic vertebrates
AG Mikhailova, D Iliushchenko, V Shamansky… - (No Title), 2020 - cir.nii.ac.jp
< jats: title> ABSTRACT < jats: p> Mutational spectrum of the mitochondrial genome (mtDNA)
fluctuates between species, however, factors responsible for this variation are mainly …
fluctuates between species, however, factors responsible for this variation are mainly …
[PDF][PDF] A mitochondrial mutational signature of temperature and longevity in ectothermic and endothermic vertebrates
AG Mikhailova, V Shamansky, AA Mikhailova… - bioRxiv, 2020 - academia.edu
Mitochondrial mutational signature is very conserved and low deviations between species
have been associated with longevity. By reconstructing species-specific mtDNA mutational …
have been associated with longevity. By reconstructing species-specific mtDNA mutational …
Mitochondrial mutation spectrum in Chordates: damage versus replication signatures, causes, and dynamics
To elucidate the primary factors shaping mitochondrial DNA (mtDNA) mutagenesis, we
reconstructed a deep 192-component mtDNA mutational spectrum using 129,100 polymorphic …
reconstructed a deep 192-component mtDNA mutational spectrum using 129,100 polymorphic …
[PDF][PDF] Risk of mitochondrial deletions is affected by the global secondary structure of the mitochondrial genome
AA Mikhailova, V Shamanskiy, K Ushakova… - BioRxiv, 2020 - academia.edu
… by the global secondary structure of the mitochondrial genome Alina A. Mikhailova …
Mikhailova#1,2, Sergei Oreshkov1, Dmitry Knorre3,4, Evgenii O. Tretiakov5, …
Mikhailova#1,2, Sergei Oreshkov1, Dmitry Knorre3,4, Evgenii O. Tretiakov5, …
A> G substitutions on a heavy chain of mitochondrial genome marks an increased level of aerobic metabolism in warm versus cold vertebrates
AG Mikhailova, D Iliushchenko, V Shamansky… - bioRxiv, 2020 - biorxiv.org
Mutational spectrum of the mitochondrial genome (mtDNA) fluctuates between species,
however, factors responsible for this variation are mainly unknown. Recently, we demonstrated …
however, factors responsible for this variation are mainly unknown. Recently, we demonstrated …