User profiles for Alisha Dhiman
Alisha DhimanPurdue University Verified email at purdue.edu Cited by 298 |
[HTML][HTML] The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53
p53 is an important tumor-suppressor protein that is mutated in more than 50% of cancers.
Strategies for restoring normal p53 function are complicated by the oncogenic properties of …
Strategies for restoring normal p53 function are complicated by the oncogenic properties of …
[PDF][PDF] PBRM1 regulates stress response in epithelial cells
Polybromo1 (PBRM1) is a chromatin remodeler subunit highly mutated in cancer, particularly
clear cell renal carcinoma. PBRM1 is a member of the SWI/SNF subcomplex, PBAF (…
clear cell renal carcinoma. PBRM1 is a member of the SWI/SNF subcomplex, PBAF (…
A potent, selective CBX2 chromodomain ligand and its cellular activity during prostate cancer neuroendocrine differentiation
Polycomb group (PcG) proteins are epigenetic regulators that facilitate both embryonic
development and cancer progression. PcG proteins form Polycomb repressive complexes 1 and …
development and cancer progression. PcG proteins form Polycomb repressive complexes 1 and …
[HTML][HTML] Functional characterization of WalRK: A two-component signal transduction system from Bacillus anthracis
Two-component signal transduction systems (TCS), consisting of a sensor histidine protein
kinase and its cognate response regulator, are an important mode of environmental sensing …
kinase and its cognate response regulator, are an important mode of environmental sensing …
BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression
Advanced prostate cancers resistant to androgen receptor antagonists are still susceptible
to nontoxic BRD9 inhibitors, making them a promising alternative for halting AR signaling in …
to nontoxic BRD9 inhibitors, making them a promising alternative for halting AR signaling in …
Exploring the interaction between Mycobacterium tuberculosis enolase and human plasminogen using computational methods and experimental techniques
Surface localized microbial enolases’ binding with human plasminogen has been increasingly
proven to have an important role in initial infection cycle of several human pathogens. …
proven to have an important role in initial infection cycle of several human pathogens. …
[PDF][PDF] Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
ARID2 is the most recurrently mutated SWI/SNF complex member in melanoma; however,
its tumor-suppressive mechanisms in the context of the chromatin landscape remain to be …
its tumor-suppressive mechanisms in the context of the chromatin landscape remain to be …
PBRM1 bromodomains associate with RNA to facilitate chromatin association
PBRM1 is a subunit of the PBAF chromatin remodeling complex, which is mutated in 40–50%
of clear cell renal cell carcinoma patients. It is thought to largely function as a chromatin …
of clear cell renal cell carcinoma patients. It is thought to largely function as a chromatin …
Enolase of Mycobacterium tuberculosis is a surface exposed plasminogen binding protein
Background Enolase, a glycolytic enzyme, has long been studied as an anchorless protein
present on the surface of many pathogenic bacteria that aids in tissue remodeling and …
present on the surface of many pathogenic bacteria that aids in tissue remodeling and …
WalRK two component system of Bacillus anthracis responds to temperature and antibiotic stress
A Dhiman, M Gopalani, R Bhatnagar - Biochemical and Biophysical …, 2015 - Elsevier
WalRK Two Component System (TCS) of Bacillus anthracis forms a functional TCS. This
report elaborates upon the WalRK genomic architecture, promoter structure, promoter activity …
report elaborates upon the WalRK genomic architecture, promoter structure, promoter activity …