User profiles for Alisha Dhiman

Alisha Dhiman

Purdue University
Verified email at purdue.edu
Cited by 298

[HTML][HTML] The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53

E Madan, TM Parker, MR Bauer, A Dhiman… - Journal of Biological …, 2018 - ASBMB
p53 is an important tumor-suppressor protein that is mutated in more than 50% of cancers.
Strategies for restoring normal p53 function are complicated by the oncogenic properties of …

[PDF][PDF] PBRM1 regulates stress response in epithelial cells

EG Porter, A Dhiman, B Chowdhury, BC Carter, H Lin… - Iscience, 2019 - cell.com
Polybromo1 (PBRM1) is a chromatin remodeler subunit highly mutated in cancer, particularly
clear cell renal carcinoma. PBRM1 is a member of the SWI/SNF subcomplex, PBAF (…

A potent, selective CBX2 chromodomain ligand and its cellular activity during prostate cancer neuroendocrine differentiation

…, S Sood, SC Ordonez‐Rubiano, A Dhiman… - …, 2021 - Wiley Online Library
Polycomb group (PcG) proteins are epigenetic regulators that facilitate both embryonic
development and cancer progression. PcG proteins form Polycomb repressive complexes 1 and …

[HTML][HTML] Functional characterization of WalRK: A two-component signal transduction system from Bacillus anthracis

A Dhiman, S Bhatnagar, P Kulshreshtha, R Bhatnagar - FEBS open bio, 2014 - Elsevier
Two-component signal transduction systems (TCS), consisting of a sensor histidine protein
kinase and its cognate response regulator, are an important mode of environmental sensing …

BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression

A Alpsoy, SM Utturkar, BC Carter, A Dhiman… - Cancer research, 2021 - AACR
Advanced prostate cancers resistant to androgen receptor antagonists are still susceptible
to nontoxic BRD9 inhibitors, making them a promising alternative for halting AR signaling in …

Exploring the interaction between Mycobacterium tuberculosis enolase and human plasminogen using computational methods and experimental techniques

A Rahi, A Dhiman, D Singh, AM Lynn… - Journal of cellular …, 2018 - Wiley Online Library
Surface localized microbial enolases’ binding with human plasminogen has been increasingly
proven to have an important role in initial infection cycle of several human pathogens. …

[PDF][PDF] Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

…, E Grossi, D Filipescu, A Alpsoy, A Dhiman… - Cell reports, 2022 - cell.com
ARID2 is the most recurrently mutated SWI/SNF complex member in melanoma; however,
its tumor-suppressive mechanisms in the context of the chromatin landscape remain to be …

PBRM1 bromodomains associate with RNA to facilitate chromatin association

SM De Silva, A Dhiman, S Sood… - Nucleic Acids …, 2023 - academic.oup.com
PBRM1 is a subunit of the PBAF chromatin remodeling complex, which is mutated in 40–50%
of clear cell renal cell carcinoma patients. It is thought to largely function as a chromatin …

Enolase of Mycobacterium tuberculosis is a surface exposed plasminogen binding protein

A Rahi, SK Matta, A Dhiman, J Garhyan… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Enolase, a glycolytic enzyme, has long been studied as an anchorless protein
present on the surface of many pathogenic bacteria that aids in tissue remodeling and …

WalRK two component system of Bacillus anthracis responds to temperature and antibiotic stress

A Dhiman, M Gopalani, R Bhatnagar - Biochemical and Biophysical …, 2015 - Elsevier
WalRK Two Component System (TCS) of Bacillus anthracis forms a functional TCS. This
report elaborates upon the WalRK genomic architecture, promoter structure, promoter activity …